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Incremental upgrades or sustained usage?

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It's best to get a card which isn't low end , or the most expensive. You want to strike a balance between the amount spent , and the speed increase the card yields based on it's price.

So instead of a rtx3090 , go for the 3080 or 3070.

However , yes it 100% depends on your workload and if a very expensive , or a very cheap card can be justified.

When it comes to GPU, is it better to buy the low-end card every year (like moving from rx 570 to 5500xt to 6700xt if I can find one) or to go balls to the wall, splurge on an insane card, and keep it for 3,4,5 years?

I currently have an RX 570 that fulfills my needs, I am thinking of upgrading in a year or two when prices stabilize. I don't need a very powerful GPU for gaming/my work.

 

 

And for anyone wondering, I cannot upgrade my CPU. It uses LGA-2011 socket, I currently have two 8-core Xeon e5-2690 v2 cpus, and as my HP z620 workstation uses a proprietary motherboard, I'll keep using those CPUs for as long as the rest of the workstation lasts since they are quite powerful for rendering. I also can upgrade my RAM, but I don't need to.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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A balls to the wall car should last 5 years, not 3.

 

Really, it's what your wallet can handle and you can justify internally.

 

My 1080Ti was my first foray into top end gear (when I bought it, only the Titan was better).   I have had it almost 4 years now and plan to upgrade next year, for 5 year keep.  

 

I personally can't see upgrading annually, having to sell or find other uses for each card. 

 

From an efficiency state... within reason I would buy a little more than you need now so as games get heavier you'll be able to play then thru the 5 year keep.  I wouldn't want to live on the edge of "just good enough" all the time.

 

Again, wallet plays a big role in this.

 

For your example,  I would wait until your components don't satisfy your needs.  Just makes sense.

 

"Do what makes the experience better" - in regards to PCs and Life itself.

 

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depends on your expectations and such

sometimes buying high end stuff and using long term and resisting the urge of trying new stuff is viable to you

sometimes buying and flipping mid-range gpu every generation is viable

 

I'm still gaming mostly on my 970, which is bought in 2016, and never own a gaming PC before, so -shrug-

i guess it's the "upgrade when you need it camp"

-sigh- feeling like I'm being too negative lately

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Just now, Dedayog said:

A balls to the wall car should last 5 years, not 3.

 

Really, it's what your wallet can handle and you can justify internally.

 

My 1080Ti was my first foray into top end gear (when I bought it, only the Titan was better).   I have had it almost 4 years now and plan to upgrade next year, for 5 year keep.  

 

I personally can't see upgrading annually, having to sell or find other uses for each card. 

 

From an efficiency state... within reason I would buy a little more than you need now so as games get heavier you'll be able to play then thru the 5 year keep.  I wouldn't want to live on the edge of "just good enough" all the time.

 

Again, wallet plays a big role in this.

 

thank you,

I'm thinking I'd be good with a nice 6800xt if I can afford it for 4-5 years. 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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It's best to get a card which isn't low end , or the most expensive. You want to strike a balance between the amount spent , and the speed increase the card yields based on it's price.

So instead of a rtx3090 , go for the 3080 or 3070.

However , yes it 100% depends on your workload and if a very expensive , or a very cheap card can be justified.

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10 minutes ago, wat3rmelon_man2 said:

When it comes to GPU, is it better to buy the low-end card every year (like moving from rx 570 to 5500xt to 6700xt if I can find one) or to go balls to the wall, splurge on an insane card, and keep it for 3,4,5 years?

I currently have an RX 570 that fulfills my needs, I am thinking of upgrading in a year or two when prices stabilize. I don't need a very powerful GPU for gaming/my work.

 

 

And for anyone wondering, I cannot upgrade my CPU. It uses LGA-2011 socket, I currently have two 8-core Xeon e5-2690 v2 cpus, and as my HP z620 workstation uses a proprietary motherboard, I'll keep using those CPUs for as long as the rest of the workstation lasts since they are quite powerful for rendering. I also can upgrade my RAM, but I don't need to.

its more about what your needs and means are. I didnt replace my gtx 770 till a year ago lol. Don't do what everyone else is doing. thats pointless. Do what you need and what you can afford. If you can afford a balls to the walls big dick card and dont mind dropping the cash? Fuck it. go for it. If your needs dont exceed the capabilities of a RX570 and are only looking to upgrade because you feel "left behind" then maybe save the money till you have a need or desire to do so. 

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1 minute ago, PhoenixFire22588 said:

its more about what your needs and means are. I didnt replace my gtx 770 till a year ago lol. Don't do what everyone else is doing. thats pointless. Do what you need and what you can afford. If you can afford a balls to the walls big dick card and dont mind dropping the cash? Fuck it. go for it. If your needs dont exceed the capabilities of a RX570 and are only looking to upgrade because you feel "left behind" then maybe save the money till you have a need or desire to do so. 

That's why i'll probably upgrade only when my RX 570 dies/becomes irrelevant.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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I always go for the --60 class cards because i play older games. If you arent the kind of person who plays all the AAA games when they come out this is perfectly viable. Only reason i even have a 1660s is because my RX 480 died, would have kept using it for many many more years if it had lasted that long, was using a used 7950 before that, and 750ti before that too, you get the idea. If your needs are currently met with an RX 570, I wouldnt bother going much higher up the product stack, a midrange GPU is fine for most people who use 1080p for a much longer time and I feel most people give it credit for.

 

On the other hand if youre into the whole 1440+ or high refresh rate, stuff thats capable of that is going to go out of date a lot faster, as leaps in performance requirements will scale much higher with more resolution.


This is all just my experience and opinions. Listen to someone else if its not what you  want to hear.

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1 minute ago, starry said:

I always go for the --60 class cards because i play older games. If you arent the kind of person who plays all the AAA games when they come out this is perfectly viable. Only reason i even have a 1660s is because my RX 480 died, would have kept using it for many many more years if it had lasted that long, was using a used 7950 before that, and 750ti before that too, you get the idea. If your needs are currently met with an RX 570, I wouldnt bother going much higher up the product stack, a midrange GPU is fine for most people who use 1080p for a much longer time and I feel most people give it credit for.

 

On the other hand if youre into the whole 1440+ or high refresh rate, stuff thats capable of that is going to go out of date a lot faster, as leaps in performance requirements will scale much higher with more resolution.


This is all just my experience and opinions. Listen to someone else if its not what you  want to hear.

a man with a plan, this guy. 

Respect.

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19 minutes ago, starry said:

I always go for the --60 class cards because i play older games. If you arent the kind of person who plays all the AAA games when they come out this is perfectly viable. Only reason i even have a 1660s is because my RX 480 died, would have kept using it for many many more years if it had lasted that long, was using a used 7950 before that, and 750ti before that too, you get the idea. If your needs are currently met with an RX 570, I wouldnt bother going much higher up the product stack, a midrange GPU is fine for most people who use 1080p for a much longer time and I feel most people give it credit for.

 

On the other hand if youre into the whole 1440+ or high refresh rate, stuff thats capable of that is going to go out of date a lot faster, as leaps in performance requirements will scale much higher with more resolution.


This is all just my experience and opinions. Listen to someone else if its not what you  want to hear.

OK, I use 1080P 144hz, mainly play multiplayer and older AAAs. RX 570 is still able to get 60+ FPS on nearly all games I play, hitting the 144 mark on a few occasionally.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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1 hour ago, wat3rmelon_man2 said:

OK, I use 1080P 144hz, mainly play multiplayer and older AAAs. RX 570 is still able to get 60+ FPS on nearly all games I play, hitting the 144 mark on a few occasionally.

The 1660 SUPER will get you that 144 fps. Can confirm. I get between 100-200 fps in like 90% of my library.

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2 hours ago, PhoenixFire22588 said:

The 1660 SUPER will get you that 144 fps. Can confirm. I get between 100-200 fps in like 90% of my library.

nice... I get barely 60fps at 4k* in something like Rise Of The Tomb Raider... mind you I do but I have to set shadows to 'high' lol... 🤷🏼

 

 

*resolution doesn't really matter when you have settings like 4x MSAA... which is nigh impossible to run on anything I suppose... ~

The direction tells you... the direction

-Scott Manley, 2021

 

 

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1 minute ago, Mark Kaine said:

nice... I get barely 60fps at 1440p in something like Rise Of The Tomb Raider... mind you I do but I have to set shadows to 'high' lol... 🤷🏼

I thought you said you use a 1080p monitor? 

 

Though I suppose if you're playing games nearly a decade old it should do a lot better than expected 

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Just now, PhoenixFire22588 said:

I thought you said you use a 1080p monitor? 

 

Though I suppose if you're playing games nearly a decade old it should do a lot better than expected 

Yes, I use a 1080P monitor, that is not my comment that is quoted.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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15 minutes ago, Mark Kaine said:

nice... I get barely 60fps at 4k* in something like Rise Of The Tomb Raider... mind you I do but I have to set shadows to 'high' lol... 🤷🏼

 

 

*resolution doesn't really matter when you have settings like 4x MSAA... which is nigh impossible to run on anything I suppose... ~

I can run my RX 570 at 2x MSAA on most games, 4x on a few, and 8 and 16 on one stably.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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I always upgrade with the settings and resolution I'm trying to attain in mind. GPUs depreciate over time (usually), so trying to future proof means you spend more for something that will rapidly degrade as new generations are released, Low tier cards are decent, but they might also require you to make sacrifices to your performance goals. Get what you need, if what exists isn't enough or is more expensive than you think it should be then you should probably wait.

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Laptop - Dell G15 | i7-11800H | RTX 3060 | 16GB CL22 3200

 

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17 minutes ago, PhoenixFire22588 said:

I thought you said you use a 1080p monitor? 

 

Though I suppose if you're playing games nearly a decade old it should do a lot better than expected 

I have a 1080p monitor, but I also have nvidia DSR, so I can play at higher resolutions, downsampled to my monitors resolution, which besides better image quality in general also gets rids of most aliasing, aka, 'jaggies'. 

 

It's quite an interesting tech, pretty sure it was a mod at first, which nvidia later integrated into their drivers as 'DSR' and now i think probably DLSS as well. 

 

10 minutes ago, wat3rmelon_man2 said:

I can run my RX 570 at 2x MSAA on most games, 4x on a few, and 8 and 16 on one stably.

in Tomb Raider, at 4k, or even 2k?

 

doubt. jpg

The direction tells you... the direction

-Scott Manley, 2021

 

 

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5 hours ago, wat3rmelon_man2 said:

When it comes to GPU, is it better to buy the low-end card every year (like moving from rx 570 to 5500xt to 6700xt if I can find one) or to go balls to the wall, splurge on an insane card, and keep it for 3,4,5 years?

I currently have an RX 570 that fulfills my needs, I am thinking of upgrading in a year or two when prices stabilize. I don't need a very powerful GPU for gaming/my work.

 

 

And for anyone wondering, I cannot upgrade my CPU. It uses LGA-2011 socket, I currently have two 8-core Xeon e5-2690 v2 cpus, and as my HP z620 workstation uses a proprietary motherboard, I'll keep using those CPUs for as long as the rest of the workstation lasts since they are quite powerful for rendering. I also can upgrade my RAM, but I don't need to.

Well if you are playing some older games that run good enough with your rx 570,i dont see the need to buy some high end gpu now.

If you want to buy for instance 3080 you need to check your PSU first will you have enough power for it.

If not that is one more cost to think about.

But going balls to the wall like you said,and not utilizing that power,would be waste of money.

 

 

 

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5 minutes ago, Mark Kaine said:

I have a 1080p monitor, but I also have nvidia DSR, so I can play at higher resolutions, downsampled to my monitors resolution, which besides better image quality in general also gets rids of most aliasing, aka, 'jaggies'. 

 

It's quite an interesting tech, pretty sure it was a mod at first, which nvidia later integrated into their drivers as 'DSR' and now i think probably DLSS as well. 

 

in Tomb Raider, at 4k, or even 2k?

 

doubt. jpg

Naaaah, not Tomb Raider, lol. 4x MSAA on Crossout, War Thunder, etc. More demanding games like Halo/Subnautica 2x, and Genshin Impact I can do 8x.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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16 minutes ago, comander said:

AA is only really meaningful at lower resolutions where discretization effects have an impact.

I kinda agree but I was just trying things out, msaa (oops, it's SSAA*) is a go with everything maxed at 4k (- very few things like shadows... I really do not see a diff between high and max/ultra usually anyway) but 2x SSAA or 4x?  nope getting drops to like 55 fps... complete no go for me (but as said I was just testing out things I don't necessarily need to max everything out) 

 

 

as for AA, it depends but while aliasing really improves using DSR, I still let it on because I *do* see the jaggies otherwise (and it really depends on the game obviously) now something like SSAA (I've mistaken that with MSAA apparently which is similar tech tho I think?) I really don't think it makes a huge difference, just very subtle and not really worth the performance impact, altho I'd probably use it at 1440p or 1080p

The direction tells you... the direction

-Scott Manley, 2021

 

 

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3 minutes ago, wat3rmelon_man2 said:

Naaaah, not Tomb Raider, lol. 4x MSAA on Crossout, War Thunder, etc. More demanding games like Halo/Subnautica 2x, and Genshin Impact I can do 8x.

Well I made a mistake it's SSAA* x2 or SSAA x4... it's basically like super sampling iirc... very demanding, so at 4k it means it's like 8k with SSAA x2 as far the GPU is concerned. 

 

 

The direction tells you... the direction

-Scott Manley, 2021

 

 

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There are 4 types of upgrading:

 

- buy best of the best every year because you don't make any compromises and always want superior experience

- buy mid range offering and keep it for 2 years and then buy the latest mid range offering again, always having decent experience

- buy new version only when new card has massive improvements (like RTX 3000 or RX 6000 series)

- buy new version of whatever tier of card when new generation doubles the performance of the last generation

 

I personally follow the last 2 upgrade paths. Point of framerate doubling is usually just as far enough that you never really experience horrible performance in games and not do it too frequently as framerate doubling doesn't happen on year to year basis. Not even with RTX 3000 series despite massive jump in performance compared to RTX 2000 series. From GTX 1080Ti to RTX 3080, the performance was pretty much doubled in majority of games, RT performance is significantly better than on RTX 2000 cards, so I decided to do it. If NVIDIA didn't make such a massive leap in performance, I'd most likely stick with it for another year and when they'd hit that doubling mark, I'd pull a trigger. It's a very functional rule that I follow for many many years now and I've basically started doing it back when Radeon HD4850 got replaced by HD5850 which doubled the framerate. of HD4850. It still works to this day. I just fly over reviews and compare my card to new one. If framerate is doubled or around that mark, I'll consider it. If it offers anything extra on top of framerate itself, even better.

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