1060 for dual 4k monitor
You can output to the monitors with prety much any graphics card that has at least HDMI 2.0 or DP 1.2.
GTX 1060 6GB is about the same as GTX 980 except it has 2GB more VRAM. In gaming it will perform almost the same.
In the software you use, the GTX 1060 6GB will actualy be better since 3D software definitely can use that extra VRAM.
I am not sure about getting AMD card for this kind of software. I know some of these can take advantage of OpenCL but with CUDA you can be sure that the graphics acceleration will 100% work with any of these.
Anyway, GTX 1060 6GB is a good choice but you may want to pick up used GTX 1070 or new if you can since 8GB of VRAM can be very helpful in your case.
If you are certain the software you use can take a full advantage of OpenCL, then AMD RX 580 8GB or Vega 56 is a better choice though.
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