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I am looking to upgrade my PC from an I3-4170 CPU, an Asus Z97-A/USB 3.1 motherboard, and two four gigabyte sticks of Kingston HyperX fury blue DDR3-1600 CL16 RAM to an I5-9600k CPU, a MSI MPG Z390 gaming plus motherboard, and two 16 gigabyte sticks of G.skill ripjaws V series DDR4-3200 CL16 RAM. Should I reinstall windows?

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Welcome to the forums!

In all the times of switching boards in testbenches on the same SSD I have never had to reinstall Windows. Just a RAM upgrade and board change is not enough to warrant that. Just make sure you download the drivers for your board and you'll be set! 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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You might as well. When upgrading that much hardware at once I prefer a fresh start so you don't run into problems with e.g. old drivers that stuck around down the line. You're probably fine, given that it's Intel to Intel, but starting fresh every now and then also isn't bad.

Crystal: CPU: i7 7700K | Motherboard: Asus ROG Strix Z270F | RAM: GSkill 16 GB@3200MHz | GPU: Nvidia GTX 1080 Ti FE | Case: Corsair Crystal 570X (black) | PSU: EVGA Supernova G2 1000W | Monitor: Asus VG248QE 24"

Laptop: Dell XPS 13 9370 | CPU: i5 10510U | RAM: 16 GB

Server: CPU: i5 4690k | RAM: 16 GB | Case: Corsair Graphite 760T White | Storage: 19 TB

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1 minute ago, Mel0nMan said:

Welcome to the forums!

In all the times of switching boards in testbenches on the same SSD I have never had to reinstall Windows. Just a RAM upgrade and board change is not enough to warrant that. Just make sure you download the drivers for your board and you'll be set! 

this isnt just a ram upgrade and a board change.

this is a full platform change.

 

its not strictly necesary, and just uninstalling the old chipset drivers should work.

but there will probably be a weird issue down the line and its better to just reinstall

I could use some help with this!

please, pm me if you would like to contribute to my gpu bios database (includes overclocking bios, stock bios, and upgrades to gpus via modding)

Bios database

My beautiful, but not that powerful, main PC:

prior build:

Spoiler

 

 

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it's defenately not necessary, but especially around such a major platform change it's a good thing to do so. both for the sake of making clean house driver-wise, and just that it's a nice opportunity to make clean house for everything else too.

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While not required, I like to do it because it cuts off any possible software issue if you need to troubleshoot anything after the upgrade.

CPU: AMD Ryzen 3700x / GPU: Asus Radeon RX 6750XT OC 12GB RAM: Corsair Vengeance LPX 2x16GB DDR4-3200
MOBO: MSI B450m Gaming Plus NVME: Corsair MP510 240GB / Case: TT Core v21 PSU: Seasonic 750W / OS: Bazzite

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