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The 1060 is getting a bit outdated - I suggest updating the GPU first. 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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4 minutes ago, Subsenie said:

Hi I’m currently running an i7 3770k and an ASUS 1060 6g strix. I’m mostly interested in gaming and streaming and would like to upgrade my system. Should I upgrade gpu or cpu first?

What games do you plan on playing?

geometry is hard
b550 > x570

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3 minutes ago, wat3rmelon_man2 said:

The 1060 is getting a bit outdated - I suggest updating the GPU first. 

The CPU is a lot more outdated than the graphics card

 

5 minutes ago, Subsenie said:

Should I upgrade gpu or cpu first?

Have you tried streaming already? If you enable NVENC and steam off the graphics card you might see some pretty good quality

I WILL find your ITX build thread, and I WILL recommend the SIlverstone Sugo SG13B

 

Primary PC:

i7 8086k - EVGA Z370 Classified K - G.Skill Trident Z RGB - WD SN750 - Jedi Order Titan Xp - Hyper 212 Black (with RGB Riing flair) - EVGA G3 650W - dual booting Windows 11 and Fedora Linux - Black and green theme, Razer brainwashed me.

Draws 400 watts under max load, for reference.

 

PSU tier list

How many watts do I need?

PSU misconceptions, protections explainedgroup reg is bad

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Just now, Subsenie said:

Pretty much AAA titles like Assassins Creed ect 

 

1 minute ago, Subsenie said:

Which gpu would you suggest? My budget is around 500$

For $500 I would get a new CPU, MOBO, and RAM. Wait for the R5 3600 to come in stock and then get it.
Then, you can snag a used 1070 for around 150 - 200 on ebay 

PCPartPicker Part List
Type Item Price
CPU AMD Ryzen 5 3600 3.6 GHz 6-Core Processor $200.00
Motherboard ASRock B450M PRO4 Micro ATX AM4 Motherboard $79.98 @ Amazon
Memory Team T-FORCE VULCAN Z 16 GB (2 x 8 GB) DDR4-3200 CL16 Memory $54.99 @ Newegg
Video Card Asus GeForce GTX 1070 8 GB STRIX Video Card $180.00
  Prices include shipping, taxes, rebates, and discounts  
  Total $514.97
  Generated by PCPartPicker 2020-12-04 09:03 EST-0500  

 

geometry is hard
b550 > x570

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I’m currently rocking an ASUS 1060 6g strix, an i7 3770k and 16gb of RAM.

My main interest is streaming and gaming (everything from Valorant to AC Valhalla). 
Should I upgrade? If yes what’s the first thing I should swap out? My budget atm is around 500$ .

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1 minute ago, Subsenie said:

I’m currently rocking an ASUS 1060 6g strix, an i7 3770k and 16gb of RAM.

My main interest is streaming and gaming (everything from Valorant to AC Valhalla). 
Should I upgrade? If yes what’s the first thing I should swap out? My budget atm is around 500$ .

Why not just stick to your orignal post? There is no need to make a new one. Anyway here is the advice I gave earlier -


 

For $500 I would get a new CPU, MOBO, and RAM. Wait for the R5 3600 to come in stock and then get it.
Then, you can snag a used 1070 for around 150 - 200 on ebay 

PCPartPicker Part List
Type Item Price
CPU AMD Ryzen 5 3600 3.6 GHz 6-Core Processor $200.00
Motherboard ASRock B450M PRO4 Micro ATX AM4 Motherboard $79.98 @ Amazon
Memory Team T-FORCE VULCAN Z 16 GB (2 x 8 GB) DDR4-3200 CL16 Memory $54.99 @ Newegg
Video Card Asus GeForce GTX 1070 8 GB STRIX Video Card $180.00
  Prices include shipping, taxes, rebates, and discounts  
  Total $514.97
  Generated by PCPartPicker 2020-12-04 09:03 EST-0500  

geometry is hard
b550 > x570

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-Topics merged-

 

Please refrain from posting duplicate topics about the same subject. 

"Put as much effort into your question as you'd expect someone to give in an answer"- @Princess Luna

Make sure to Quote posts or tag the person with @[username] so they know you responded to them!

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2 hours ago, Subsenie said:

How would I go about enabling NVENC?

If you're using OBS it's in your stream settings, just a check box.

 

If you're streaming via Nvidia shadowplay, it's the default streaming method.

I WILL find your ITX build thread, and I WILL recommend the SIlverstone Sugo SG13B

 

Primary PC:

i7 8086k - EVGA Z370 Classified K - G.Skill Trident Z RGB - WD SN750 - Jedi Order Titan Xp - Hyper 212 Black (with RGB Riing flair) - EVGA G3 650W - dual booting Windows 11 and Fedora Linux - Black and green theme, Razer brainwashed me.

Draws 400 watts under max load, for reference.

 

PSU tier list

How many watts do I need?

PSU misconceptions, protections explainedgroup reg is bad

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9 minutes ago, Subsenie said:

Thanks !

do you think a gtx 2070 would be bottlenecked by my i7 3770k ?

depends on the resolution, refresh rate, and games in question. there are a lot of circumstances where the CPU is a little underpowered, but plenty of cases where it's fine.

I WILL find your ITX build thread, and I WILL recommend the SIlverstone Sugo SG13B

 

Primary PC:

i7 8086k - EVGA Z370 Classified K - G.Skill Trident Z RGB - WD SN750 - Jedi Order Titan Xp - Hyper 212 Black (with RGB Riing flair) - EVGA G3 650W - dual booting Windows 11 and Fedora Linux - Black and green theme, Razer brainwashed me.

Draws 400 watts under max load, for reference.

 

PSU tier list

How many watts do I need?

PSU misconceptions, protections explainedgroup reg is bad

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23 minutes ago, Subsenie said:

Which cpu would you recommend?

Well if you're strictly gaming, a ryzen 5 3600 from the used market is a good choice, since they seem to be scarce at the moment on retail sites. Ryzen 5000 supply is expected to materialize a bit in a month or so, and if you're holding out for top tier gaming performance it would be worth it. 

 

But holding on to your i7 for the time being and waiting for better prices/availability is the best move in my opinion. In fact, I also recommend waiting on that graphics card upgrade as well, for the same reason.

I WILL find your ITX build thread, and I WILL recommend the SIlverstone Sugo SG13B

 

Primary PC:

i7 8086k - EVGA Z370 Classified K - G.Skill Trident Z RGB - WD SN750 - Jedi Order Titan Xp - Hyper 212 Black (with RGB Riing flair) - EVGA G3 650W - dual booting Windows 11 and Fedora Linux - Black and green theme, Razer brainwashed me.

Draws 400 watts under max load, for reference.

 

PSU tier list

How many watts do I need?

PSU misconceptions, protections explainedgroup reg is bad

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17 hours ago, Fasauceome said:

Well if you're strictly gaming, a ryzen 5 3600 from the used market is a good choice, since they seem to be scarce at the moment on retail sites. Ryzen 5000 supply is expected to materialize a bit in a month or so, and if you're holding out for top tier gaming performance it would be worth it. 

 

But holding on to your i7 for the time being and waiting for better prices/availability is the best move in my opinion. In fact, I also recommend waiting on that graphics card upgrade as well, for the same reason.

What kind of motherboard would go well with the Ryzen 3600 or 5000?

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21 minutes ago, Subsenie said:

What kind of motherboard would go well with the Ryzen 3600 or 5000?

budget B450 motherboards are a prime candidate for 3000 series CPUs. 5000 series CPUs will see more widespread support from board partners on 400 series motherboards in early 2021, but for now ASRock has BIOS versions available for the CPUs. Otherwise, some budget A520 motherboards are good choices, if you don't mind cutting CPU overclocking.

I WILL find your ITX build thread, and I WILL recommend the SIlverstone Sugo SG13B

 

Primary PC:

i7 8086k - EVGA Z370 Classified K - G.Skill Trident Z RGB - WD SN750 - Jedi Order Titan Xp - Hyper 212 Black (with RGB Riing flair) - EVGA G3 650W - dual booting Windows 11 and Fedora Linux - Black and green theme, Razer brainwashed me.

Draws 400 watts under max load, for reference.

 

PSU tier list

How many watts do I need?

PSU misconceptions, protections explainedgroup reg is bad

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