storage See the first movie uploaded to DNA of living cells

[captain_to_fire]

4 minutes ago, AHaskin14 said:

Interesting thought. The "read" picture is certainly different from the original with a few darker pixels here and there. This is essentially an unplanned mutation no? Imagine what sorts of problems can occur down the road when this technology is used for things other than data storage. Really cool, but really scary.

The thing with CRISPR is that the it can can through a DNA segment with extreme precision and accuracy unlike the old school use of restriction enzymes so there would be way less errors. But CRISPR is also a dark horse. What scientists know about the potential benefits and hazards (a double edged sword) of this discovery is just at the tip of the iceberg. I suggest you watch the video I linked because the folks of Kurzgesagt YouTube channel did an amazing job explaining CRISPR. Personally, I'd think DNA storage has a long way to go and people of the PC master race are just fine with their existing SATA or NVMe SSD and no need use their spit just yet for storage. Right now, DNA storage is more of a proof of concept for the future rather than something beneficial right now. 

[AHaskin14]

16 minutes ago, hey_yo_ said:

The thing with CRISPR is that the it can can through a DNA segment with extreme precision and accuracy unlike the old school use of restriction enzymes so there would be way less errors. But CRISPR is also a dark horse. What scientists know about the potential benefits and hazards (a double edged sword) of this discovery is just at the tip of the iceberg. I suggest you watch the video I linked because the folks of Kurzgesagt YouTube channel did an amazing job explaining CRISPR. Personally, I'd think DNA storage has a long way to go and people of the PC master race are just fine with their existing SATA or NVMe SSD and no need use their spit just yet for storage. Right now, DNA storage is more of a proof of concept for the future rather than something beneficial right now. 

Fully agreed, being  just a proof of concept (and an extremely cool one at that). I'll surely watch the video when I get home from work

[Shreyas1]

I think its cool how the pictures are different due to mutations. That wouldn't be very cool for data though.

[captain_to_fire]

Just now, Shreyas1 said:

I think its cool how the pictures are different due to mutations. That wouldn't be very cool for data though.

It was an animated GIF that I can't save. Go to the CNET link.

[Shreyas1]

1 minute ago, hey_yo_ said:

It was an animated GIF that I can't save. Go to the CNET link.

The problem here is that even if you try to make the cells not mutate, they will. The problem is that the cells will multiply, and each generation will have mutations. Correct me if I'm wrong, but I think bacteria can share their DNA, corrupting data even more. This seems very bad for long term storage IMO. 

[captain_to_fire]

30 minutes ago, Shreyas1 said:

Correct me if I'm wrong, but I think bacteria can share their DNA, corrupting data even more. This seems very bad for long term storage IMO. 

Yes they can. Bacteria can share info with other bacteria through their plasmid, a small circular DNA beside their chromosome. If the storage media (agar plate or broth) is properly autoclaved at 121°C/15 psi for 15 minutes and proper lab aseptic techniques are done in a properly irradiated Biosafety Level II cabinet, there's less likely chance that the edited bacteria can talk to other bacteria of different species. This is why at the moment, DNA storage is more of a proof of concept rather than something beneficial.

 

But the other uses of CRISPR at the moment like treating incurable diseases is something humanity needs now.

30 minutes ago, Shreyas1 said:

The problem here is that even if you try to make the cells not mutate, they will. The problem is that the cells will multiply, and each generation will have mutations.

They do. Sometimes cells do mutate even by their own metabolic byproducts or by ionizing radiation like UV rays. But most cells can repair minor mutations. In eukaryotic cells like humans, if a mutation can't be fixed, the cell will commit suicide also known as apoptosis or programmed cell death by themselves or get killed by the immune system cells namely Cytotoxic T cells and Natural Killer Cells.

Edited July 13, 2017 by hey_yo_

[SpaceGhostC2C]

13 hours ago, hey_yo_ said:

Just imagine the future where office documents are stored in DNA samples while immersed in Tris-acetate EDTA buffer inside a test tube connected to a computer. Or in a more dystopian future, the US government mass producing genetically enhanced super soldiers from the US army going to battle against China's genetically enhanced super soldiers. The latter is way more creepy.

Or we can come back to Earth with a simpler implication: forget backups, save to one bacteria and let her replicate into a small colony. A few drops of a bacteria-friendly soup and you have thousands/millions of copies of your data.

 

But then comes the risk: one silly mutation with the wrong resilience and your colony goes corrupt. Was it Tuttle or Buttle?  

[captain_to_fire]

6 minutes ago, SpaceGhostC2C said:

Or we can come back to Earth with a simpler implication: forget backups, save to one bacteria and let her replicate into a small colony. A few drops of a bacteria-friendly soup and you have thousands/millions of copies of your data.

 

But then comes the risk: one silly mutation with the wrong resilience and your colony goes corrupt. Was it Tuttle or Buttle?  

That's why the idea is cool but not practical at the moment. I'd still pick a Samsung 960 Evo over having some bacteria in an agar plate store my data.

[VerticalDiscussions]

But...

 

HOW !!??!!??

 

But this is cool:

 

 

 

[Doobeedoo]

Now 4K plz. 

[ARikozuM]

2 hours ago, hey_yo_ said:

That's why the idea is cool but not practical at the moment. I'd still pick a Samsung 960 Evo over having some bacteria in an agar plate store my data.

ADD: Agar-DNA drives? I wouldn't mind!

[ARikozuM]

4 hours ago, SpaceGhostC2C said:

But then comes the risk: one silly mutation with the wrong resilience and your colony goes corrupt. Was it Tuttle or Buttle?  

It was 404.

[Master Disaster]

And on the same earth as scientists are recording movies into DNA a large portion of people genuinely believe the earth is flat.

[captain_to_fire]

5 hours ago, ARikozuM said:

ADD: Agar-DNA drives? I wouldn't mind!

That thing will stink. Nutrient agar or any other enrichment media (like violet red bile agar) smells awful. Imagine putting an agar plate for DNA storage inside a PC with FX-9590. 

[Beskamir]

Applicable video on the subject from the perspective of a biologist.

[ARikozuM]

1 hour ago, hey_yo_ said:

That thing will stink. Nutrient agar or any other enrichment media (like violet red bile agar) smells awful. Imagine putting an agar plate for DNA storage inside a PC with FX-9590. 

I've got tons of agar plates, though... What am I supposed to do with them? Science? Pfft, that's for the biologists!

 

[FPSwithaWacomTablet]

This method is a surefire way to eliminate thoughtcrime

 

 

 

/s