Is it normal ?
Go to solution
Solved by Atmos,
seem you are not alone
http://linustechtips.com/main/topic/301832-borderlands-2tps-horrible-fps-w-xfired-r9-290s/
this user also have troubles with AMD cards and Borderlands 2 game
Borderlands, as far as it's delves into PhysX go, is terrible.
@OP: If you have it enabled and at full, using guns that are corrosive or slag can cause so much of the damn liquid to pool up that it causes your game to chug along at 10fps. The issue is that it backtracks the work load to the cpu end of things when it cant handle the processes, putting un-needed stress on a system. Only way to fix it is to reduce your PhysX quality to it's lowest setting, as the game still requires it to be enabled in some way to work correctly.

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