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Just now, Cynestal said:

So i want to buy a MSI Radeon™ R9 380 Twin Frozr V / 4GB GDDR5 / OC / (R9 380 GAMING 4G) GPU and my MOBO is a MSI Socket 1150 B85-G43 Gaming (B85-G43 GAMING) and has a Intel CPU so i dont know if my gpu can be in my mobo.

You will be fine with a single AMD card in that motherboard. 

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yes, they will all work together. its more about whether the slot is pci-e(all modern GPUs are) or not than which brand the gpu is(otherwise nvidia GPUs also won't work).

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2 hours ago, Cynestal said:

So i want to buy a MSI Radeon™ R9 380 Twin Frozr V / 4GB GDDR5 / OC / (R9 380 GAMING 4G) GPU and my MOBO is a MSI Socket 1150 B85-G43 Gaming (B85-G43 GAMING) and has a Intel CPU so i dont know if my gpu can be in my mobo.

I'd recommend getting an RX 480 since it's the successor to the 380. It has a lot better performance and better efficiency.

 

Of course most GPUs will work with your motherboard since it has a PCI-E x16 slot. 

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2 hours ago, legacy99 said:

You will be fine with a single AMD card in that motherboard. 

But perhaps OP should get the RX 480 since it is the successor to the 380.

Judge a product on its own merits AND the company that made it.

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50 minutes ago, AluminiumTech said:

But perhaps OP should get the RX 480 since it is the successor to the 380.

I would suggest OP learn how PC work first, with a question like this it's obvious he has no clue.

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