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Is there any possibility for an AMD Radeon RX 600 series?

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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there's always a possibility, whether or not it will come is another thing. I'm sure there will be some sort of low end graphics card series from amd coming.

AMD blackout rig

 

cpu: ryzen 5 3600 @4.4ghz @1.35v

gpu: rx5700xt 2200mhz

ram: vengeance lpx c15 3200mhz

mobo: gigabyte b550 auros pro 

psu: cooler master mwe 650w

case: masterbox mbx520

fans:Noctua industrial 3000rpm x6

 

 

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5 hours ago, mariushm said:

No, there's 5500, 5600 ... if anything they can make a 5400 or a 5300. 

why make those cards, there's alreadys 5xx cards that fit that area, a card that performs around a 5700xt and based on rdna2 but is less than a 6700 makes more sense than a 5400 or 5300. 

AMD blackout rig

 

cpu: ryzen 5 3600 @4.4ghz @1.35v

gpu: rx5700xt 2200mhz

ram: vengeance lpx c15 3200mhz

mobo: gigabyte b550 auros pro 

psu: cooler master mwe 650w

case: masterbox mbx520

fans:Noctua industrial 3000rpm x6

 

 

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2 hours ago, Letgomyleghoe said:

why make those cards, there's alreadys 5xx cards that fit that area, a card that performs around a 5700xt and based on rdna2 but is less than a 6700 makes more sense than a 5400 or 5300. 

because 

* 5xx  cards are older ... making 6xx cards would confuse people, would make people think they're worse than 5xxx because 5xxx is higher than 5xx or 6xx

 

* 5xx was based on GCN, which is older. making another series with that architecture would mean keeping/extending support for GCN in the drivers and making fixes and stuff for much longer time, instead of focusing on improving drivers for 5xxx and 6xxx with rdna and rdna2 - usually when there's 2-3 generations old, they "freeze" the drivers for those cards and keep support in the drivers for them, but new drivers won't bring improvements except fixes to get some games working at launch.

 

* pointless to release something on old GCN when new rdna2 is used in both major consoles and all game engines and developers will optimize their games for RDNA x  and care less about cards that began to be released in 2016 (for GCN4 cards like RX 4xx and RX 4xx)

 

* the 5xx cards were made on 14nm (except rx590 which is made on 12nm), which means more silicon area used compared to 7nm process - 7nm process is more expensive but you get more chips out of a round 20-30cm wafer. Makes little sense to go back to something that would consume more power and be bigger and harder to cool.

 

* they can scale down current designs, or reuse chips that aren't good enough for a 5500x if the market demands something even slower than a 5500x

 

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