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Unless you are using one of the following applications you take advantage of openCL so by extent multiple GPUs (unless of course they are in SLI) https://en.wikipedia.org/wiki/List_of_OpenCL_applications. Although there are exceptions where games use PhysX and you hypothetically (wouldn't recommend) use two cards. Also it is important to note that most of these OpenCL applications only support one GPU even though they could support multiple GPUs, but they haven't added the appropiate code so they only support one.

TL;DR: You can't use OpenCL for multiple GPUs in most consumer applications (including all games that I am aware of, couldn't find any that support it).

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