Weird issue with RX6700XT
Download the latest optional GPU drivers from AMD, the newest B550 drivers from MSI, and DDU from Guru3D.
Disconnect your internet and run DDU, reboot.
Install your GPU drivers, reboot.
Install your chipset drivers, reboot.
plug your internet in, and you should be golden.
On my 6700XT (reference), I can run almost everything short of CP2077 and RDR2 maxed out at 1440p with no problems. And my home rig is almost a carbon copy of what you're running.
I did do a slight undervolt though because the reference cooler might look cool, but it's not awesome.
That hissing is called coil whine, it's extremely common in GPU's. My GeForce 5200 Ultra did it, my GTX 670 did it, so does my 5700XT in my office workstation.

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