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My pc for a couple months now won’t boot half the time after a little bit of fiddling with it I can get it to boot and will work fine but if I restart it I can almost guarantee it will not turn on again and same if I were to shut it down and then turn it on it will only turn on maybe 20% of the time but when it turns on it will work fine untill you turn it off I have no idea what’s wrong and I have no trick to get it to turn on ether it’s totally random I’m thinking it’s the motherboard because also for a couple months now windows 10 can not keep the time correct it is always a few hours slow 

 

- I changed  the cmos battery it did not help

 

pc build-

ryzen 7 3700x

asrock b450 mobo (don’t know exact model)

16 gb ballistic ram 3000mhz

600w psu 

gtx 1070

 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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What drives do you have? 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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2 minutes ago, Mel0nMan said:

What drives do you have? 

I have a 500gb wd nvme ssd as boot drive and 3 other sata ssd 2 500gb and 1 250gb for storage 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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5 minutes ago, Savage2988 said:

I have a 500gb wd nvme ssd as boot drive and 3 other sata ssd 2 500gb and 1 250gb for storage 

Ah, lots! 

Do they all show up in your BIOS? Likely DEL, ESC, F9, or F12 to enter. Also if it's exactly 2 hours or exactly 3 hours or whatever slow, that's an issue with your timezone setting in Windows, right click the clock on the taskbar and click the correct timezone

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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8 minutes ago, Mel0nMan said:

Ah, lots! 

Do they all show up in your BIOS? Likely DEL, ESC, F9, or F12 to enter. Also if it's exactly 2 hours or exactly 3 hours or whatever slow, that's an issue with your timezone setting in Windows, right click the clock on the taskbar and click the correct timezone

Yes when I can get the pc to boot they do show up in the bios and I’ve checked the time zone setting and it’s all good I have to sync the time again to get it to show the right time then a couple hours later it will be wrong 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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40 minutes ago, BiotechBen said:

So what happens when you exit BIOS startup.

I can’t even boot to bios when it doesn’t boot it will do absolutely nothing but when it does boot it will boot like nothing even happened 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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1 hour ago, Savage2988 said:

I can’t even boot to bios when it doesn’t boot it will do absolutely nothing but when it does boot it will boot like nothing even happened 

That sounds like it could be a memory issue, when it doesn't go into BIOS, does it boot loop (repeated on and off)

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12 hours ago, BiotechBen said:

That sounds like it could be a memory issue, when it doesn't go into BIOS, does it boot loop (repeated on and off)

Nope it won’t boot loop it literally won’t do anything it’s like it’s not even plugged in 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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12 hours ago, BiotechBen said:

That sounds like it could be a memory issue, when it doesn't go into BIOS, does it boot loop (repeated on and off)

I had extra ddr4 around and didn’t fix it 

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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17 hours ago, BiotechBen said:

This now sounds like a motherboard issue or a PSU issue. Go through all the cables and give them a good push into their sockets.

Okay I will do that and also I have a spare psu I can try but I’m thinking it’s the mobo too so I ordered another one just in case but if it turns out to me the psu I’ll just return the mobo

My Gaming Rig - Ryzen 7 3700X (4.4ghz all cores @ 1.3v) - Asus Strix GTX 1080 TI - 32gb Corsair Vengeance LPX 3200mhz - Asus TUF Gaming X570-Plus (Wifi) - Evga Supernova 750 GT - Deepcool Castle 360ex - 1Tb WD Blue NVME SSD (Boot) - NZXT H9 Flow

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