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Yes, it would work with that motherboard. M.2 NVME SSD's use the PCIE interface, which this motherboard supports:

Quote

1 x M.2 Socket 3, , with M Key, type 2242/2260/2280 storage devices support (both SATA & x2 PCIE mode)*1

https://www.asus.com/Motherboards-Components/Motherboards/PRIME/PRIME-H310M-A-R2-0/techspec/

 

The x2 PCIE does mean the SSD can only run at up to 2000MB/s, instead of its max of 3400MB/s

"We're all in this together, might as well be friends" Tom, Toonami.

 

mini eLiXiVy: my open source 65% mechanical PCB, a build log, PCB anatomy and discussing open source licenses: https://linustechtips.com/topic/1366493-elixivy-a-65-mechanical-keyboard-build-log-pcb-anatomy-and-how-i-open-sourced-this-project/

 

mini_cardboard: a 4% keyboard build log and how keyboards workhttps://linustechtips.com/topic/1328547-mini_cardboard-a-4-keyboard-build-log-and-how-keyboards-work/

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9 minutes ago, oldmotherboard said:

ASUS Prime H310M - A R2.0

E15471_PRIME_H310M-A_R2.0_UM_V2_WEB.pdf (asus.com)

PDF page 6 - Storage.

Yes, your motherboard supports M.2 SSDs with a length of 2280.

My build:

CPU

Intel Core i7 9700 8x 3.00GHz So.1151

 

CPU cooler

be quiet! Shadow Rock Slim

 

Motherboard

MSI B360-A PRO Intel B360 So.1151 Dual Channel DDR4 ATX

 

RAM

16GB (4x 4096MB) HyperX FURY black DDR4-2666

 

GPU

8GB Gigabyte GeForce RTX2070 WindForce 2X 3xDP/HDMI

 

SSD

500GB Samsung 970 Evo Plus M.2 2280

 

HDD

4000GB WD Red WD40EFRX Intellipower 64MB 3.5" (8.9cm) SATA 6Gb/s

 

Power Supply

bequiet! Straight Power 750W Platinum

 

Case

Fractal Design Define R6
3x bequiet! Silent Wings 3 PWM

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