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Budget (including currency): none yet

Country: Mexico

Games, programs or workloads that it will be used for: emulation of OS and some games like assesins creed or sekiro

Other details (existing parts lists, whether any peripherals are needed, what you're upgrading from, when you're going to buy, what resolution and refresh rate you want to play at, etc): I have a ryzen 2400g, 8x2 ram gskill aegis 3000, MB asrock b450m pro4, gpu 5600xt, nvme 1tb adata swordfish

I wish yo know what to upgrade first cause I can only upgrade one thing once each semester

 

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Welcome to the forums!

First of all, you don't really need an upgrade to any of those for what you say you're doing. However, my recommendation for first upgrade if you insist is the 2400g.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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Welcome to the forums!!!

4 minutes ago, Mel0nMan said:

However, my recommendation for first upgrade if you insist is the 2400g.

Indeed I would go with upgrading the 2400G. Also, in the future, between RAM to a higher frequency as Ryzen favors high DRAM frequencies and also the motherboard depending on which CPU you are going to upgrade to since the VRMs don't appear to be the greatest.

 

CPU Cooler Tier List  || Motherboard VRMs Tier List || Motherboard Beep & POST Codes || Graphics Card Tier List || PSU Tier List 

 

Main System Specifications: 

 

CPU: AMD Ryzen 9 5950X ||  CPU Cooler: Noctua NH-D15 Air Cooler ||  RAM: Corsair Vengeance LPX 32GB(4x8GB) DDR4-3600 CL18  ||  Mobo: ASUS ROG Crosshair VIII Dark Hero X570  ||  SSD: Samsung 970 EVO 1TB M.2-2280 Boot Drive/Some Games)  ||  HDD: 2X Western Digital Caviar Blue 1TB(Game Drive)  ||  GPU: ASUS TUF Gaming RX 6900XT  ||  PSU: EVGA P2 1600W  ||  Case: Corsair 5000D Airflow  ||  Mouse: Logitech G502 Hero SE RGB  ||  Keyboard: Logitech G513 Carbon RGB with GX Blue Clicky Switches  ||  Mouse Pad: MAINGEAR ASSIST XL ||  Monitor: ASUS TUF Gaming VG34VQL1B 34" 

 

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15 minutes ago, julioaqm said:

Budget (including currency): none yet

Figure one out.

 

15 minutes ago, julioaqm said:

I have a ryzen 2400g, 8x2 ram gskill aegis 3000, MB asrock b450m pro4, gpu 5600xt, nvme 1tb adata swordfish

Honestly the heaviest game you got is Sekiro and its pretty GPU bound. No upgrades for now, but if you want to upgrade anyway a 5600x would be an easy route. Remember to update your BIOS before installing the CPU.

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