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Budget (including currency): 850 Euros

Country: Greece

Games, programs or workloads that it will be used for: Light video editing and games like fortnite minecraft valorant splitgate

Other details:I dont need an cooler cuz im gonna use the stock and i have nothing so i need to buy everything

Curent Build Plan: Ryzen 5 1600AF,3200mhz cl16 16gb,A 1650,Msi B450 Tomahawk Max II , Seagate Baracudda 2tb , kingston a2000 500gb ,Artic F12 120nm fan x2 for 815 Euros here in greece

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You’ll want a GPU. Also you need a power supply. GTX 960 can be found pretty cheap as a temporary gpu, for a psu I recommend a 450-600 watt or so.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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2 minutes ago, Mel0nMan said:

You’ll want a GPU. Also you need a power supply. GTX 960 can be found pretty cheap as a temporary gpu, for a psu I recommend a 450-600 watt or so.

He mentioned a 1650

7 minutes ago, Tayxin said:

Curent Build Plan: Ryzen 5 1600AF,3200mhz cl16 16gb,A 1650,Msi B450 Tomahawk Max II , Seagate Baracudda 2tb , kingston a2000 500gb ,Artic F12 120nm fan x2 for 815 Euros here in greece

 

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Just now, Latvian Video said:

He mentioned a 1650

 

Ah my bad

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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1 hour ago, Mel0nMan said:

You’ll want a GPU. Also you need a power supply. GTX 960 can be found pretty cheap as a temporary gpu, for a psu I recommend a 450-600 watt or so.

I will prob get an be quite straight power 9 500w just forgot to menton

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1 hour ago, Mel0nMan said:

You’ll want a GPU. Also you need a power supply. GTX 960 can be found pretty cheap as a temporary gpu, for a psu I recommend a 450-600 watt or so.

Also here we dont hav any gpu like the gtx 960 we have the 710 the 1030 as temporary cards

 

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1 hour ago, Tayxin said:

Budget (including currency): 850 Euros

Country: Greece

Games, programs or workloads that it will be used for: Light video editing and games like fortnite minecraft valorant splitgate

Other details:I dont need an cooler cuz im gonna use the stock and i have nothing so i need to buy everything

Curent Build Plan: Ryzen 5 1600AF,3200mhz cl16 16gb,A 1650,Msi B450 Tomahawk Max II , Seagate Baracudda 2tb , kingston a2000 500gb ,Artic F12 120nm fan x2 for 815 Euros here in greece

Anything less then 3rd gen ryzen you should just ignore and go for 10th gen intel since itll obliterate zen and zen+ cpus, maybe go for the 10400(f) or 11400(f)

 

Youll also want a board with a semi decent vrm, maybe the b560 pro vdh or whatever 8 phase you can find

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2 hours ago, Somerandomtechyboi said:

Anything less then 3rd gen ryzen you should just ignore and go for 10th gen intel since itll obliterate zen and zen+ cpus, maybe go for the 10400(f) or 11400(f)

 

Youll also want a board with a semi decent vrm, maybe the b560 pro vdh or whatever 8 phase you can find

Here those things can cost up to 200$ and the board is like 150$ so like about half my budget is spent on these things 

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2 hours ago, Somerandomtechyboi said:

Anything less then 3rd gen ryzen you should just ignore and go for 10th gen intel since itll obliterate zen and zen+ cpus, maybe go for the 10400(f) or 11400(f)

 

Youll also want a board with a semi decent vrm, maybe the b560 pro vdh or whatever 8 phase you can find

Im gonna explain the pricing real quick bc i need advice : any i5 is hella expensive and the r5 1600af in my humble opinion and based on things i 've seen is a pretty good cpu. The whole build is well thought of and i have thought of most stuff i came here to ask about gpu's but pricing here is lower.F.e. I can find a 1650 for abt 245 Euros  whereas in amazon,newegg i can find the same card for 400.So if you have any suggestions i woud love to hear them!

 

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