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Hello everybody,

I'm currently rocking the following specs:

- Cpu Ryzen 9 3900xt

- Mobo Asus Strix X570-F gaming

- Gpu Rog strix 2070 Super

- Ram 64gb 3600mhz cl16 Gskill Neo's

- Psu Corsair 1200 watt 80 platinum

 

I was curious what you guys recommend as a next upgrade(s). Myself I was thinking my gpu would be the first to swap out when the prices get better. Still would love to hear any tips.

 

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I think that the GPU would be the next logical upgrade since that's really the bottleneck in your build, may I recommend a 3070, 3070TI, or 3080?

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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1 minute ago, Mel0nMan said:

I think that the GPU would be the next logical upgrade since that's really the bottleneck in your build, may I recommend a 3070, 3070TI, or 3080?

I was thinking the same, probably a 3070ti or 3080 when the prices get less insane.

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Perhaps more storage space like another NVMe or even a HDD for bulk storage for games. 

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5 minutes ago, DullJoker said:

I was thinking the same, probably a 3070ti or 3080 when the prices get less insane.

And then after that I would do cpu but that’s like in the far future. 

https://pcpartpicker.com/list/Qm9Mwc

 

 

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Upgrade right now/when GPU prices come down? I wouldn't personally bother upgrading anything in that PC, it's already pretty much on the high end side of things and unless you absolutely need to have your all games run at ultra 4k, it should still easily handle most things and keep you going until the next generation that will likely be coming out next year as it will have been 2 years and its usually 2 years between generations.

 

Honestly, that computer could probably do just fine without an upgrade for at least 4 years (2 generations of GPUs), IMO, as long as you're ok reducing quality/resolution to 1080p to keep a constant 60+fps in essentially everything. After that, it would only require a GPU upgrade, unless there's massive advancements on the CPU side of things (do remember, if you want to upgrade the CPU, your only upgrade path is the 5000 series, after that you'll have to buy a new motherboard and RAM).

CPU: AMD Ryzen 3700x / GPU: Asus Radeon RX 6750XT OC 12GB RAM: Corsair Vengeance LPX 2x16GB DDR4-3200
MOBO: MSI B450m Gaming Plus NVME: Corsair MP510 240GB / Case: TT Core v21 PSU: Seasonic 750W / OS: Bazzite

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24 minutes ago, DullJoker said:

Hello everybody,

I'm currently rocking the following specs:

- Cpu Ryzen 9 3900xt

- Mobo Asus Strix X570-F gaming

- Gpu Rog strix 2070 Super

- Ram 64gb 3600mhz cl16 Gskill Neo's

- Psu Corsair 1200 watt 80 platinum

 

I was curious what you guys recommend as a next upgrade(s). Myself I was thinking my gpu would be the first to swap out when the prices get better. Still would love to hear any tips.

 

What monitor do you have? If it is less than 4k or 144Hz, you could upgrade that.

 

Then you would have a reason to upgrade your GPU to something like a GeForce RTX 3080.

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