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I was wondering is it possible to have 2 different gpus, most motherboards have 4 Gpu sockets, so i thought have 2 Quadro RTX 6000 and 2080Ti, while using UE4 switch on Quadro RTX 6000, leave 2080Ti switch off while using Blender and UE4, then when i want to test see how game performs switch off the 2 Quadro RTX 6000, and then turn on the 2 2080Ti gpus is it possible to do.

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You want to have 2x 2080 Ti (maybe in SLI?) and 2x RTX Quadro 6000 in the same system?

 

While possible you'd need a beefy Threadripper or Skylake-X CPU with a bunch of PCIe Lanes and at least a Corsair AX1600i to power it all.

 

In this the RTX 6000 Quadros would only serve for hardware acceleration while you'd use the 2080 Ti SLI to image display.

 

But this would be so overkill and so expensive to put together lol

Personal Desktop":

CPU: Intel Core i7 8700 @4.45ghz |~| Cooling: Cooler Master Hyper 212X |~| MOBO: Gigabyte Z370M D3H mATX|~| RAM: 16gb DDR4 3333mhzCL16 G.Skill Trident Z |~| GPU: nVidia Founders Edition GTX 1080 Ti |~| PSU: Corsair TX650M 80Plus Gold |~| Boot:  SSD WD Green M.2 2280 240GB |~| Storage: 1x3TB HDD 7200rpm Seagate Barracuda + SanDisk Ultra 3D 1TB |~| Case: Fractal Design Meshify C Mini |~| Display: Toshiba UL7A 4K/60hz |~| OS: Windows 10 Pro.

Luna, the temporary Desktop:

CPU: Intel Core i7 10700KF @ 5.0Ghz (5.1Ghz 4-core) |~| Cooling: bq! Dark Rock 4 Pro |~| MOBO: Gigabyte Z490 UD |~| RAM: 32G Kingston HyperX @ 2666Mhz CL13 |~| GPU: AMD Radeon RX 6800 (Reference) |~| PSU: Corsair HX1000 80+ Platinum |~| Windows Boot Drive: 2x 512GB (1TB total) Plextor SATA SSD (RAID0 volume) |~| Linux Boot Drive: 500GB Kingston A2000 |~| Storage: 4TB WD Black HDD |~| Case: Cooler Master Silencio S600 |~| Display 1 (leftmost): Eizo (unknown model) 1920x1080 IPS @ 60Hz|~| Display 2 (center): BenQ ZOWIE XL2540 1920x1080 TN @ 240Hz |~| Display 3 (rightmost): Wacom Cintiq Pro 24 3840x2160 IPS @ 60Hz 10-bit |~| OS: Windows 10 Pro (games / art) + Linux (distro: NixOS; programming and daily driver)
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1 hour ago, James Aplin said:

I was wondering is it possible to have 2 different gpus, most motherboards have 4 Gpu sockets, so i thought have 2 Quadro RTX 6000 and 2080Ti, while using UE4 switch on Quadro RTX 6000, leave 2080Ti switch off while using Blender and UE4, then when i want to test see how game performs switch off the 2 Quadro RTX 6000, and then turn on the 2 2080Ti gpus is it possible to do.

Short answer: yes, it is possible to run multiple different GPU's at the same time in one system, for computational workloads.

 

For powering games or driving the monitors, I believe the GPU's need to be identical and hooked up in SLI. I don't think you can SLI different models of GPU together.

 

Also, the use case you are describing, using Quadro's for work and RTX 2080Ti for gaming seems way too complicated. You can theoretically switch devices on and off in device manager, but this is very cumbersome. If you are only using the 2080Ti's for gaming and driving the monitors, and the Quadro's exclusively for computational workloads, I think it can be done without ever switching anything off in device manager.

 

Why not just use two 2080ti's for both workloads and call it a day? What is the Quadro giving you that you really need?

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