Recommendations for a workstation?
I probably would go 5950X instead, because for those type of workloads it likely will make a difference, and the prices for it have come down a lot. The other day I had seen it listed for somewhere around $530 (I'll try to find the listing, it might have gone out of stock), so for the ~$200 price increase you get a lot more performance in most 3D design applications, and you probably won't have to think about upgrading for a while.
For a motherboard, there are three things that you need to think about. 1.) Does the motherboard have an adequate VRM solution for the CPU you want? Most motherboards about the $160 price point will be more than enough for a 5950X, but it's not guaranteed. 2.) Does the motherboard have all the features that you want? If you need a motherboard that supports x8/x8 for example, you need to make sure the board you are getting supports x8/x8. Same thing applies with connectors, does it have enough SATA, does it have front panel USB Type C, does it have enough M.2 slots, etc. 3.) Does the motherboard have any known issues that might affect you. The Gigabyte B550 Master, for example, has a dual BIOS implementation that makes the board almost unusable for most overclockers, so while the rest of the board might be awesome, without heavy modification the board is not worth using. Once you find boards that meet all those criteria, go for the cheapest one there. The motherboard, practically speaking, is just a fancy cable, so you shouldn't really spend more money on a board that doesn't have any advantages you'd see, and you might as well put that money into faster RAM, better storage, etc. As for X570 vs B550, for most people there really aren't many advantages for going X570 over B550. X570 offers a couple more M.2 slots at gen 4 speeds, and has better VFIO support if you're a virtualization enthusiast. If you don't need either of those things, you might as well save money and go for a B550 board, since dollar for dollar they tend to be built better than their X570 counterparts. I'll help you with finding a board, but knowing exactly what you need and what you don't would be beneficial.
For RAM, I'd probably go for 64GB, but if you can find a 2x16GB kit that you know is single rank it would still let you go for higher capacity in the future without having to sacrifice speed.

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