Triple monitor issue

[ThyFeared]

I'm currently running a triple monitor setup as of the moment. Each time I want to go ahead and play a game my main monitor will decide to black screen then boom come back up after a couple of seconds. The issue is persistent and will constantly keep happening in the middle of gaming/browsing (sometimes on the browsing). The odd thing is, is I unplug another monitor making it a dual setup works perfect no issues at all. This black screen issue will happen a ton during gaming but little during outside of it.

I've tried the following:

• Re-Installing GPU Drivers (Clean Install)
• Re-seated the GPU
• Swapped the GPU to the lower PCI-e slot
• Tried about every single outlet I could to make sure it's not an electrical problem
• Re-seated RAM just in case

At this point it's getting quite frustrating and I'm running out of ideas

 

Specs are as follows:

Ryzen 7 3700x

EVGA 1080ti

32GB RAM

EVGA Super Nova 650 G5

 

Main Monitor: Acer Predator XB3 27" 1440p 240Hz

2nd Monitor: Acer - XF270H 27"

3rd Monitor: Dell S2716DGR 1440p 144Hz 27"

 

Appreciate the help