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The Xeon cpu is a bit better but I’d go with the first choice. Better gpu option, more ram out of the box, cpu is still pretty good nowadays and you could put a 128gb ssd and 1 or 2tb hdd in there for games easily.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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18 minutes ago, Mel0nMan said:

The Xeon cpu is a bit better but I’d go with the first choice. Better gpu option, more ram out of the box, cpu is still pretty good nowadays and you could put a 128gb ssd and 1 or 2tb hdd in there for games easily.

the psu does not seem to have a 8 pin cable, so would a dual molex to 8 pin work ?

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That's a tough choice.

 

At first glance, I'd go with option 2. I've used a Xeon X5650 system and it certainly ran a lot better than my old i5 4440 one (which admittedly is a bit slower than the 4570, but not a ton). You also get the SSD and graphics card up front, so all you need to invest in is some more RAM.

 

Of course, the graphics card is only a 2GB one, which is important for more modern titles, but the X5650 can handle modern games way better than the i5 4570, so you're losing out in modern titles either way.

 

And if the PSU for the other one doesn't have a PCIe output to begin with, that just makes me lean even more towards the Xeon. It would certainly have a better upgrade path for a future GPU.

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2 minutes ago, notBogglete said:

the psu does not seem to have a 8 pin cable, so would a dual molex to 8 pin work ?

Ok In that case go with the Xeon one… 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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2 minutes ago, notBogglete said:

EVGA 500 W1 80+ 500 Watt brand new in box

That one is low-priority D-Tier on the PSU Tier List, so not a good PSU, but it probably wouldn't blow up your computer. If you're on a tight budget, it is what it is. My last computer had an ApexGaming PSU with a 9600K and 2060 Super and it worked fine, but it isn't recommended for computers with a dedicated graphics card.

 

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12 minutes ago, notBogglete said:

what about a XILENCE RedWing R7 XP600R7 600w for the same price 

Also D-Tier, although I had to look through the spreadsheet to find it (it doesn't seem to be listed on the forum post yet).

 

I'd go with the EVGA one over that, because at least the EVGA has an 80+ certification (even if it is only the basic 80+).

 

 

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4 minutes ago, YoungBlade said:

Also D-Tier, although I had to look through the spreadsheet to find it (it doesn't seem to be listed on the forum post yet).

 

I'd go with the EVGA one over that, because at least the EVGA has an 80+ certification (even if it is only the basic 80+).

 

 

idk but i think i found a better deal

CPU - Intel Xeon E2620 V2 (6 cores /12 threads ) Socket 2011

Cooler : DeepCool Gamma Archer 120 mm

Motherboard : X79G V1.2 Socket 2011

GPU : Radeon SAPPHIRE NITRO+ RX 570 4GB GDDR5

RAM : 2x8 - 16 GB DDR3 1866 Ghz

SSD: Patriot Burst 120 GB

PSU:Deepcool DN650 650W

for:426$

 

and trow in my 500b hdd

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On 8/21/2021 at 10:04 PM, notBogglete said:

idk but i think i found a better deal

CPU - Intel Xeon E2620 V2 (6 cores /12 threads ) Socket 2011

Cooler : DeepCool Gamma Archer 120 mm

Motherboard : X79G V1.2 Socket 2011

GPU : Radeon SAPPHIRE NITRO+ RX 570 4GB GDDR5

RAM : 2x8 - 16 GB DDR3 1866 Ghz

SSD: Patriot Burst 120 GB

PSU:Deepcool DN650 650W

for:426$

 

and trow in my 500b hdd

Where the hell are you even getting these deals?

 

Aliexpress?

Locally?

Any other deals youve found?

 

That does look like a really good deal, only issue being the 2620 v2 is a snail and only boosts to 2.6ghz

 

If you get that one id suggest swapping the cpu for a 1650 v2 since it has an unlocked multi and can be overclocked, i dont suggest the sandy bridge cpus since they are pretty inefficient compared to ivybridge (v2) cpus

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47 minutes ago, Somerandomtechyboi said:

Where the hell are you even getting these deals?

 

Aliexpress?

Locally?

Any other deals youve found?

 

That does look like a really good deal, only issue being the 2620 v2 is a snail and only boosts to 2.6ghz

 

If you get that one id suggest swapping the cpu for a 1650 v2 since it has an unlocked multi and can be overclocked, i dont suggest the sandy bridge cpus since they are pretty inefficient compared to ivybridge (v2) cpus

Local ebay variant 

 

And i contacted the seller for the i5 and he can throw in a compatible psu for no extra cost so i guess il get that one

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