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New build losing peripherals


Hello if anyone could please help it would be greatly appreciated. I am helping a friend with a gaming rig that she put together and have been having the same issue after over a week of troubleshooting. The issue that I am having is that when I try to load an application (League of Legends, WoW, etc.) I lose connection to my mouse, keyboard, and display. I have replaced each individual component to test, I have formatted the drive and reinstalled Windows and reinstalled all of the applications, I updated the BIOS and all drivers for each hardware component, tried running the system out of the case, and in the case. 


I am at a loss and have found nothing useful digging through forums. I came across someone that suggested flashing the original BIOS back onto the mobo, but the system will not allow a BIOS downgrade.


Any help at all would be greatly appreciated.


Here are the contents of the build:


Ryzen 7 2700X

MSI B-450 Tomahawk

16GB Corsair Vengeance RGB Pro DDR4-3200 (2 x 8GB)

Samsung Evo 860 500GB 2.5" SSD

EVGA GeForce GTX 1660 Ti 6GB SC Ultra Gaming GPU

Corsair RM 750W full modular PSU

Asus ROG Strix Helios ATX Full Tower Case



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