Looking for Program/Application for Audio
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Solved by LogicalDrm,
This isn't really going to be easy. First you need software to be able to select audio output device. Most media and VOIP software can do this, games etc. not. Then you need virtual audio cable's and/or different audio devices to direct audio to each monitor. So you can't use HDMI audio from GPU to both. They need to use different audio devices.

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