Two DDR4 kits
Yeah, it's safe, though depending on what's in the kits there could be some incompatibility between them.
On the back of both of those kits there should be a version number that tells what memory IC they have. If it's the same version number, both kits should work together no problem (unless it's ver. 4.32, those can sometimes have compatibility issues with themselves). If they're different, I'd run a memory stability test to make sure they're stable (something like Memtest86 should do the job).
Longevity and performance for doing this are fine, in fact you might get slightly better performance because it's dual rank effectively rather than single rank. Doing this, even if they aren't compatible with each other and fail the stability test (or refuse to boot like what's more common if the chips don't like each other) won't harm them, it just means that they didn't like running together.

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