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Surestgarlic2
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Keep using Windows 10 unless you want to switch to Linux. If you want to run Windows applications, keep it on 10. If you want to branch out, Linux. I recommend Mint or Ubuntu for that use case if you do go Linux.

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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1 minute ago, Mel0nMan said:

Keep using Windows 10 unless you want to switch to Linux. If you want to run Windows applications, keep it on 10. If you want to branch out, Linux. I recommend Mint or Ubuntu for that use case if you do go Linux.

would this be worth adding another 4 gb ram so I have eight

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1 minute ago, Surestgarlic2 said:

would this be worth adding another 4 gb ram so I have eight

Yep. 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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2 minutes ago, Surestgarlic2 said:

would this be worth adding another 4 gb ram so I have eight

Yes, and get an SSD if you do not have one in there.

 

It won't run Windows 11?   Tested or theory?

"Do what makes the experience better" - in regards to PCs and Life itself.

 

Onyx: Ryzen 7 7800X3D / Gigabyte B650 AORUS Pro AX / ASRock Taichi 7900xtx OC / G. Skill Flare X5 6000CL36 64GB (4x16GB) / Samsung 980 1TB x3 / Super Flower Leadex V Plat Pro 1000 / EK-AIO 360 Basic w/ Silent Wings fans / Fractal Design North XL (black mesh) / LG - UltraGear 45" OLED QHD 240Hz / Mackie CR5BT / SteelSeries Arctis Nova Pro / Cherry MX Board 3.0 / Logitech G502 - https://valid.x86.fr/my9nnr

 

7800X3D - PBO +200, CO -30 all cores, 4.90GHz all core, 5.05GHz single core, Cinebench 23: 18401 multi, 1779 single

 

Khaleesi: Ryzen 5 5600X3D (+200, -30) - ASRock B550M Pro4 - G. Skill Ripjaws V 16GB 3200CL16 - Asus Prime 9060XT 16GB - Samsung 980 1TB + Crucial MX500 1TB - Cudy AX3000 PCIe Wifi 6 - EVGA SuperNOVA 650 P2 - Thermalright Frozen Notte RGB 360 White V2 - NZXT H6 Flow RGB White - LG 34" 3440x1440

 

NAS/Plex/Game Server  Ryzen 9 5900XT 16c/32t - Gigabyte B550M AORUS Elite AX - TeamGroup T-Force Vulcan 64GB 3200CL16 - MSI 1050Ti 4GB - Crucial P3 Plus 500GB + TeamGroup MP44L 2TB (Game) + WD Red Plus 4TBx2 (Plex) - TP-Link AC1200 PCIe Wifi - EVGA SuperNOVA 650 P2 - Thermalright Peerless Assassin 120SE - ASUS Prime AP201 - Currently Hosting: Enshrouded x2, Hytale, Icarus, Windrose. Project Zomboid, Dune Awakening.

 

Sage: Ryzen 7 7800X3D (+200, -30) - Gigabyte B650 Gaming X V2 - ASRock Steel Legend 7900GRE - G. Skill Flare X5 32GB 6000CL32 - TeamGroup MP44L 2TB - Super Flower Leadex Platinum SE 1000w - NZXT H5 Elite

 

Emma: i9 9900K @5.2Ghz - Gigabyte Z370 AORUS Gaming 5 - MSI 6900XT Gaming X Trio - G. Skill Ripjaws V 32GB 3200CL16 - 750 EVO 512GB + 2x 860 EVO 1TB (RAID0) - Super Flower Combat FG 850w - Thermaltake Water 3.0 Ultimate 360 - Fractal Design Define R6 - TP-Link AC1900 PCIe Wifi

 

GF Rig: Steam Deck 512GB OLED, Vizio 43" 4K TV

 

Extra parts: ASUS 6650XT - Gigabyte 1080Ti - Cooler Master Q300L - Gigabyte 450w PSU - Super Flower Leadex V Plat Pro 850w

 

OnePlus Ecosystem: 

OnePlus 11 5G - 16GB RAM, 256GB NAND, Eternal Green. OnePlus Watch 2 - Radiant Steel, OnePlus Buds Pro 2 - Eternal Green

3D Printing: 

Bambu Lab X1 Carbon, AMS, AMS2 Pro (thank you MicroCenter!)

Other Interesting Tech:

- 2021 Volvo S60 Recharge T8 PHEV Polestar Engineered - 415hp/495tq 2.0L 4cyl. turbocharged, supercharged and electrified.

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17 minutes ago, Surestgarlic2 said:

it said it wouldn't and I can't get the leaked build because the google drive is maxed out on all of the links

 

29 minutes ago, Surestgarlic2 said:

would this be worth adding another 4 gb ram so I have eight

What brand is the laptop and what RAM is it running? (If it's HP and DDR3 I have a 4gb dimm that I could give you from one of my old laptops)

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