Coil Whine in GPU
What I can say from personal experience: I had an RTX 2070 from ASUS that produced quite a substantial amount of coil whine at high framerates (almost as bad as my old R9 290), paired with a Pure Power 8 630W from be quiet - pretty old, not great PSU. After I built my new system (and in turn, a new PSU - RM650x), while some coil whine was still present, it got drastically lower. That being said, I've also ran my old previously mentioned 290 with a couple different PSUs (granted not with the one I have now), and it had pretty much the same amount of coil whine regardless.
So basically, a better PSU could help, but it's not guaranteed.
Now, regardless of reducing coil whine, a new PSU could be a good investment. The CX500 is quite old and wasn't particularly great even at launch. I'd definitely suggest replacing it especially if you plan on upgrading your CPU/GPU in the near future.

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