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yes but it won't be optimal, you'll get better performance out of 2 8gb 1866mhz.

(◣_◢) Ryzen 5 3600,   Aorus X370 K7,   XPG 16GB 3200,   Gigabyte 2070 Windforce Corsair RM650x,   LG 32GK650F-B 31.5" 144Hz QHD FreeSync VA,   Kingston 120GB SSD,   Samsung 1TB 860 QVO,   2TB HDD,   Fractal Design Meshify C,   Corsair K63 Wireless,   Corsair Gaming M65 PRO,   Audio Technica ATH M50x,   Windows 10 ProCorsair H100x 240mm.  (◣_◢)

(◣_◢) Ryzen 5 1600,   Noctua NH-L12S,   Gigabyte GTX 1060 6G,   ASUS Prime B350 Plus,   HyperX Fury 8GB DDR4 (2666MHz - 1.3v),   SilverStone ET550-B,   Kingston 120GB SSD 2TB HDD,   Cougar MX330,   Windows 10 Pro.  (◣_◢)

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Will it work, yes probably, will it work well, no.  RAM must be the same size for Dual Channel to run properly, and running 2 sticks in single channel can give you anywhere from 10-30+% performance reduction in games compared to if you had 2 matched sticks running in Dual Channel.

Primary Rig:

CPU: AMD 7800X3D @ Stock PBO - Mobo: Gigabyte X670E AORUS Master

2 x 48GB G.Skill Trident Z Royal 6400MHz CL32 1.35V @ 6200MHz CL28-37-32-30 1.5V (still tuning)

CPU Cooler: EK AIO that will be being replaced when I get the chance - PSU: eVGA P2 1200W

GPU: Gigabyte RTX 4090 Gaming OC @ either 2595MHz @ 900mV or 2970MHz @ 1070mV

Case: Thermaltake View 91 - SSDs/HDDs: 1 Samsung 980 Pro 2TB, 2 990 Pro 2TB M.2s, 1 990 Pro 4TB M.2, 1 TeamGroup Cardea Z440 2TB M.2, 1 Seagate EXO X10 10TB HDD

Monitor: Samsung Odyssey G9 49" Super-Ultrawide 240Hz Monitor

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