My mouse(s) are not working correctly

[Mr.Scruffy the great]

So I have been using the early 2014 iMac for most things anyone would need to use a computer for. minecraft web surfing, steam etc, but I have noticed a recent problem. occasionally, only a few times in the past has this happened, but the left click of the mouse freezes until I shut down the computer. Occasionally this takes a few tries. The mouse I use is the razor abyssus, and when not available the 2004 mac mouse. When it first started freezing the left click I tried to use different mice, even wireless bluetooth ones, but it works on none of them. Now it has stopped working but will not start when I reset. Other options I have tried are using different usb ports, powering down entirely, using different types of input(trackpads) using different keyboards including 2008 apple keyboard, and 2014 wireless mac. The one I normally use is the 1998 apple pro keyboard. If there is anything I can do before i figure out how to remove from it from my to take it to the apple store would help.