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This morning I noticed that my laptop was having quite a bit of trouble running Crossout - everything turned to low or off and I was getting below 20 fps. Usually I get around 50 fps on medium. Checked GPU-z and saw that it was never clocking above 214 mhz. Is there any way to fix this? Thanks!

image.thumb.png.ed60462d30a533a59b76d857683102b5.png

 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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Have you chosen a power saving plan? What GPU temps are you hitting while playing?  

GAMER 

SPEC: HYTE Y60 White/Black + Custom ColdZero ventilation sidepanel – AMD Ryzen 7 9800X3D + ASUS ROG RYUJIN III 360 – G.SKILL Trident Z5 Neo RGB DDR5-6000 64GB CL30-40-40-96 – ASUS RTX ROG ASTRAL 5080 OC – ASUS ROG STRIX B850-E GAMING Wi-Fi – Samsung EVO Plus 1TB, Samsung EVO Plus 1TB – Corsair HX1200i
GEAR: Samsung Odyssey Neo G9 G95NC 57" – ASUS ROG Harpe Ace Aim Lab Edition Wireless – ASUS ROG Claymore II Wireless –
ASUS ROG Sheath BLK LTD – FiiO K7 DAC/AMP + Beyerdynamic DT 770 PRO X (Limited Editon), Edifier S351DB, Steelseries Arctis Nova Pro Wireless


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SPEC: Corsair 4000D Airflow TG – AMD Ryzen Threadripper 1950X – Corsair Vengeance LPX 128GB (CMK32GX4M2D3000C16 x4) – ASUS GeForce GT710 1GB – ASUS ROG Zenith Extreme – ROG AREION 10Gbps – Toshiba XG6 1TB, WD 256GB, Kioxia 256GB – Corsair HX750
GEAR: Philips 346B1C 34" – Logitech MX Keys – Logitech M705 – Jabra Evolve2 75

 

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Quote

Is it plugged in? Is it turned on? Are you sure? No, really. 

First thing I would check is to make sure the charger is seated correctly, just unplug it a replug in and see if it makes a difference.

why no dark mode?
Current:

Watercooled Eluktronics THICC-17 (Clevo X170SM-G):
CPU: i9-10900k @ 4.9GHz all core
GPU: RTX 2080 Super (Max P 200W)
RAM: 32GB (4x8GB) @ 3200MTs

Storage: 1TB WD Blue NVMe SSD
Displays: Internal 1080p@300Hz, Asus ROG XG-17 1080p@240Hz (G-Sync), Gigabyte M32U 4k@144Hz (G-Sync), External Laptop panel (LTN173HT02) 1080p@120Hz

Asus ROG Flow Z13 (GZ301ZE):
CPU: i9-12900H @ Up to 5.0GHz all core
- dGPU: RTX 3050 Ti 4GB

- eGPU: Radeon 6850m XT XGm 16GB
RAM: 16GB (8x2GB) @ 5200MTs

Storage: 1TB NVMe SSD, 1TB MicroSD
Display: Internal 1200p@120Hz

Minisforum MS-A2:

CPU: Ryzen 9 9955HX

RAM: 63GB (2x32GB) DDR5 @ 5600MTs

Storage: 2x 1TB Various NVMe SSD in RAID 1, 4x 10TB HGST Enterprise HDD in RAID Z1

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Just now, Mnky313 said:

First thing I would check is to make sure the charger is seated correctly, just unplug it a replug in and see if it makes a difference.

I think you replied to a signature 

GAMER 

SPEC: HYTE Y60 White/Black + Custom ColdZero ventilation sidepanel – AMD Ryzen 7 9800X3D + ASUS ROG RYUJIN III 360 – G.SKILL Trident Z5 Neo RGB DDR5-6000 64GB CL30-40-40-96 – ASUS RTX ROG ASTRAL 5080 OC – ASUS ROG STRIX B850-E GAMING Wi-Fi – Samsung EVO Plus 1TB, Samsung EVO Plus 1TB – Corsair HX1200i
GEAR: Samsung Odyssey Neo G9 G95NC 57" – ASUS ROG Harpe Ace Aim Lab Edition Wireless – ASUS ROG Claymore II Wireless –
ASUS ROG Sheath BLK LTD – FiiO K7 DAC/AMP + Beyerdynamic DT 770 PRO X (Limited Editon), Edifier S351DB, Steelseries Arctis Nova Pro Wireless


Home LAB
SPEC: Corsair 4000D Airflow TG – AMD Ryzen Threadripper 1950X – Corsair Vengeance LPX 128GB (CMK32GX4M2D3000C16 x4) – ASUS GeForce GT710 1GB – ASUS ROG Zenith Extreme – ROG AREION 10Gbps – Toshiba XG6 1TB, WD 256GB, Kioxia 256GB – Corsair HX750
GEAR: Philips 346B1C 34" – Logitech MX Keys – Logitech M705 – Jabra Evolve2 75

 

Racing SIM

GEAR: Sim-Lab GT1 EVO Sim Racing Cockpit + Integrated Vario Triple mount – Svive Racing D1 Seat – MSI 325CQRXF 32" x3 – Simagic Alpha Mini + Simagic GT4 (Dual Clutch) – CSL Elite Pedals V2 – Logitech K400 Plus

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1 minute ago, BetteBalterZen said:

I think you replied to a signature 

yeah, his sig refers to making sure it's plugged in properly. It was intentional 

why no dark mode?
Current:

Watercooled Eluktronics THICC-17 (Clevo X170SM-G):
CPU: i9-10900k @ 4.9GHz all core
GPU: RTX 2080 Super (Max P 200W)
RAM: 32GB (4x8GB) @ 3200MTs

Storage: 1TB WD Blue NVMe SSD
Displays: Internal 1080p@300Hz, Asus ROG XG-17 1080p@240Hz (G-Sync), Gigabyte M32U 4k@144Hz (G-Sync), External Laptop panel (LTN173HT02) 1080p@120Hz

Asus ROG Flow Z13 (GZ301ZE):
CPU: i9-12900H @ Up to 5.0GHz all core
- dGPU: RTX 3050 Ti 4GB

- eGPU: Radeon 6850m XT XGm 16GB
RAM: 16GB (8x2GB) @ 5200MTs

Storage: 1TB NVMe SSD, 1TB MicroSD
Display: Internal 1200p@120Hz

Minisforum MS-A2:

CPU: Ryzen 9 9955HX

RAM: 63GB (2x32GB) DDR5 @ 5600MTs

Storage: 2x 1TB Various NVMe SSD in RAID 1, 4x 10TB HGST Enterprise HDD in RAID Z1

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1 minute ago, Mnky313 said:

yeah, his sig refers to making sure it's plugged in properly. It was intentional 

Ah, haha right, my bad 😛 

GAMER 

SPEC: HYTE Y60 White/Black + Custom ColdZero ventilation sidepanel – AMD Ryzen 7 9800X3D + ASUS ROG RYUJIN III 360 – G.SKILL Trident Z5 Neo RGB DDR5-6000 64GB CL30-40-40-96 – ASUS RTX ROG ASTRAL 5080 OC – ASUS ROG STRIX B850-E GAMING Wi-Fi – Samsung EVO Plus 1TB, Samsung EVO Plus 1TB – Corsair HX1200i
GEAR: Samsung Odyssey Neo G9 G95NC 57" – ASUS ROG Harpe Ace Aim Lab Edition Wireless – ASUS ROG Claymore II Wireless –
ASUS ROG Sheath BLK LTD – FiiO K7 DAC/AMP + Beyerdynamic DT 770 PRO X (Limited Editon), Edifier S351DB, Steelseries Arctis Nova Pro Wireless


Home LAB
SPEC: Corsair 4000D Airflow TG – AMD Ryzen Threadripper 1950X – Corsair Vengeance LPX 128GB (CMK32GX4M2D3000C16 x4) – ASUS GeForce GT710 1GB – ASUS ROG Zenith Extreme – ROG AREION 10Gbps – Toshiba XG6 1TB, WD 256GB, Kioxia 256GB – Corsair HX750
GEAR: Philips 346B1C 34" – Logitech MX Keys – Logitech M705 – Jabra Evolve2 75

 

Racing SIM

GEAR: Sim-Lab GT1 EVO Sim Racing Cockpit + Integrated Vario Triple mount – Svive Racing D1 Seat – MSI 325CQRXF 32" x3 – Simagic Alpha Mini + Simagic GT4 (Dual Clutch) – CSL Elite Pedals V2 – Logitech K400 Plus

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5 minutes ago, BetteBalterZen said:

Have you chosen a power saving plan? What GPU temps are you hitting while playing?  

Yep, it's on high performance, and GPU is set to the RX 560. 

What the horse considers play, the monkey considers business...

But to Tom, it's all foolery. 

 

 

 

 

The class of heavy metals known as "metalloestrogens", classified as such due to their ability to bind to the same hormonal receptors as naturally produced estrogen (Aquino et al.), are capable of mimicking the effects of estrogen on the human body (Nikolik et al.). Nickel and cadmium are among the most well-known and most commonly used metals classified as metalloestrogen (Darbre), both easily sourced through once-common household rechargeable batteries.

Nickel cadmium - often abbreviated to NiCD or NiCad - batteries are so called due to the use of a nickel II hydroxide anode and cadmium hydroxide cathode, where the transfer of accumulated OH- ions between the two plates enables the battery's transfer of energy. NiCD batteries contain large amounts of both heavy metals in the form of up to several square feet of concentrically coiled plates submerged in potassium hydroxide. Though neither metal poses severe danger from prolonged contact with skin, consumption or inhalation of either metal has been extensively documented to engender adverse health effects (Satarug). 

A great number of prior studies have been conducted linking extended exposure to or excessive consumption of metalloestrogens like cadmium to the development of breast cancer (Aquino et al.) - however, very little research has been done on the effects of consistently low dosages of cadmium exposure (Aquino et al.). Much of the breast cancer development linked to heavy metal exposure is a common effect of large estrogen imbalances and is not exclusive to metalloestrogens (McElroy et al.). Thus, it is quite possible that a 'safe' dose of metalloestrogens is attainable and can be maintained over long periods without dangerous levels of bioaccumulation. 

Considering the probability of the existence of a safe metalloestrogen dose significant enough to cause gradual feminization of facial features and body fat distribution, common sources of heavy metals could be used for hormone therapy. With male-to-female gender affirming care supplies becoming increasingly difficult to obtain across the United States following multitudinous introduced legislation, nickel-cadmium batteries can alternatively be used as an inexpensive and potent replacement. 

 

Works Cited

      Aquino NB, Sevigny MB, Sabangan J, Louie MC. The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30(3):189-224. doi: 10.1080/10590501.2012.705159. PMID: 22970719; PMCID: PMC3476837.

      Rollerova, E., Urbancikova, N. Intracellular estrogen receptors, their characterization and function (Review). https://www.sav.sk/journals/endo/full/er0400f.pdf.

      Nikolic J, Sokolovic D. Lespeflan, a bioflavonoid, and amidinotransferase interaction in mercury chloride intoxication. Ren Fail. 2004 Nov;26(6):607-11. doi: 10.1081/jdi-200037149. PMID: 15600250.

      Darbre PD. Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J Appl Toxicol. 2006 May-Jun;26(3):191-7. doi: 10.1002/jat.1135. PMID: 16489580.

      Satarug S, Garrett SH, Sens MA, Sens DA. Cadmium, environmental exposure, and health outcomes. Environ Health Perspect. 2010 Feb;118(2):182-90. doi: 10.1289/ehp.0901234. PMID: 20123617; PMCID: PMC2831915.

      McElroy JA, Shafer MM, Trentham-Dietz A, Hampton JM, Newcomb PA. Cadmium exposure and breast cancer risk. J Natl Cancer Inst. 2006 Jun 21;98(12):869-73. doi: 10.1093/jnci/djj233. PMID: 16788160.

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