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So I've just built my PC, installed Windows 10 Pro using the Rufus USB stick method and with a fresh new system I can't download anything, when trying to run anything I get the same constant message "windows defender application control to block this app", I've disabled Windows Defender and I can't disable Secure Boot in the BIOS. 

Done a fresh install twice and activated my key but still nothing, this is the most problematic PC I have ever seen.

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https://linustechtips.com/topic/884640-cant-install-anything/
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