Dual CPU Boards
You should be able to use one cpu with no problems. On certain boards, however, this will limit the available number of PCIe lanes. In addition, you will only be able to use 1 cpu worth of RAM slots. Work will be automatically distributed between the two CPUs, but keep in mind your workload; many tasks are better suited to the faster fewer cores of a single cpu system than many cores, and will fail to fully take advantage of the many cores of a dual cpu system.
These boards are typically designed for intense workstation workloads, many of which can take advantage of tremendous quantities of ram, such as intensive video / audio production and scientific computation.
Also, remember that only Xeon cpus can be used in dual CPU configurations.

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