ASRock Rack has a new motherboard on the way that you might find interesting, the ROMED4ID-2T. It's basically a motherboard that uses a new form factor, Deep-ITX and can house an AMD EYPC 7002 processor. It's quite significant as it's one of the smallest EYPC 7002 motherboard that has appeared on the market. Want 64 cores and 128 threads on a tiny board? This is for you. Plus there are a load of Slim SAS SFF-8654 PCIE 4.0 x8 ports on it for expansion. The rear IO is terrible, but this is a server board. There is an M.2 2280 PCIE 4 slot on it however, so that might be a way of adding some USB ports or even intergrated WIFI if you find an M-Key to E-Key convertor.
Here's the current details on the board via ASRock Rack's website: https://www.asrockrack.com/general/productdetail.asp?Model=ROMED4ID-2T#Specifications
Should make for some rather bonkers builds.