I had this issue before I installed the software. My fans would be fine and then they would spool up just randomly due to temp spikes, so it literally sounded like it would spike to 50 degrees. Contacted AMD, they said it doesn't happen when doing desktop things like chrome and word so it must be the motherboard software, low and behold it is. MSI now have a slight grudge against me or they might just be as stumped as I am as I haven't had a reply from them in a few (working) days.
And yes, I have uninstalled all programs that use the temp sensor for the CPU.