The only overclocks I have are on the GPU (+100 Core +500 Memory, which I've had for a few weeks now and it worked fine) and the XMP profile for RAM. The temperatures never went past 70C for both the CPU and the GPU according to MSI Afterburner and HWMonitor so it's not that either. After disabling the XMP profile it doesn't seem to shut down, but GPU usage in game (i tested AC:Origins since it always shuts down when trying to load a savegame) is all over the place an it maxes out at 95%. Also there appears to be some awful coil whine as soon as the game starts (coil whine.m4a).
I really don't know what to think here. I'm still not convinced it's the power supply suddenly failing. Any help would be appreciated.