Using tubing which was too big for my whole watercooling loop. When I wanted to add a CPU waterblock, the tubing got lose and got fluid all over my Graphics card and fans. Luckily, the card survived.
And my current mistake is not drilling holes for my radiator. I was lazy and just used double sided tape to fix the radiator and fans. but now the air just passes by the small holes on the outside of the radiator.