A mismatch between RGB and YCbCr would be very obvious, many colors would be completely different (dark grey would become green, white would become bright pink, etc.) It wouldn't cause subtle things like what the OP is seeing.
Using YCbCr mode on an RGB input image looks like this:
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The kind of text fringing the OP is seeing could be caused by poor subpixel rendering settings (incorrect ClearType setup), but could also be from image filters applied by the monitor, such as sharpness setting or things like that. The colors all look crisp now, but i am trying to figure out why i am only gettin 80-90 frames in overwatch and destiny when i used to be getting 140 no problem. w
I went into my settings and for some reason it was set to YCBCR, i switched it to RGB and every thing seems good.