Since they are old laptop drives, I wouldn't count on them being reliable so at the very least I would be putting them in a RAID either a RAID 10 or RAID 5.
RAID 10 would likely give you better performance, unless you have a dedicated RAID card, as it has much less overhead. But raid 10 will also give you less space, you will only have 320GB of usable storage. Also with RAID 10, since all drives have an exact duplicate, if 1 drive fails, it will warn you, but just keep on trucking and using the other drive with no downtime.
RAID 5 would give you more space usable, 480GB, but would likely have lower performance for you as it requires a lot more CPU overhead for it to calculate parity data. A dedicated RAID card would probably actually make this the faster option though. Also if a drive were to die you would have some downtime as you would need to get a new drive and run the rebuild process.