It is absolutely possible, my friend asked me about it and we did it. We even built a docking station for it from old PC cases. He liked it while it lastes, but sacraficing the Wi-FI card for it made it a little les justifyable after a year. In the end, he bought a computer.
Note: we later on added 2 fans to each side for better airflow and to cool down the GPU. We failed to document it. However, de dock is up for sale right now if you want