I have recently bought a 8GB ram stick. I previously had 2x4GB ram sticks in slot 2 and 4 of my motherboard (same colour slots for dual channel). It started giving me errors, the red lights on the motherboard would light up for DRAM. then for VGA, and it eventually got fixed after fixing the ram better in slot 1 and running the memory setup, although I still cannot explain how I got it to work as I have done absolutely nothing other than keep resetting and choosing to go into the bios without any changes. Computer ran smooth, it recognised that I had 3 out of 4 slots occupied and 16 GB of ram. The next day, I run into a "disk read" error and then it changed to "Select proper boot device" . I have Windows 10 installed on my Kingston 256GB SSD, and it worked pretty well until now, the SSD is 6 months old at best (bought it in July). I have looked into BIOS and it is first priority in the booting list (set as "UEFI Hard Disk"). Right now, the only solution I can find is re-installing Windows, but I really want to know how my RAM can mess this whole thing up. As of now, ram setup is like this: My motherboard has 2 black slots(slots 2 and 4) and 2 white slots(slots 1 and 3) - the black slots are occupied by my 2x4 GB Hyperx Fury DDR4 2133MHz, and slot 1 is taken up by my Hyperx Savage DDR4 2133MHz. I have read that it is not necessary to use dual channel on a dual channel motherboard, but I haven't found any instance in which there were 3/4 slots used.
EDIT: I should also had that I had bought the ram from a friend, so it had been in use before. He made sure to ask me if my other ram sticks were DDR4 at 2133MHz.
Specs:
Windows 10
motherboard: 150M Bazooka (has dual channel)
Geforce GTX 1660
Intel Core i5-6402P
ZM600-LE
2x4 GB Hyperx Fury ram cards DDR4 2133MHz
1x8GB Hyperx Savage DDR4 2133MHz
Kingston 256GB SSD
WD Blue 1 TB HDD