I'm still daily drive my first build. Trinity A10 APUs had just hit the market, and I managed to snag one with a damaged box for $25 off. Still run that same chip, motherboard, case, and PSU. I've replaced the case and heatsink fans with Noctuas, upgraded RAM sticks, second HDD, and upgraded from a Radeon HD 7770 after it bit the dust to a GTX 970 that a buddy of mine gave me for this last Christmas.
The build itself was fairly straight forward, since I did myself a few favors by buying a case with plenty of room, a motherboard with a good layout, and semi-modular PSU. I did have some problems POSTing at first, but the issue cleared on it's own after I reseated the RAM and gave the power connections a solid wiggle, so not sure what caused it there.
It was my second scrapyard build that I learned 3 major lessons: Don't use cheap no-name PSUs, make sure you're properly grounded, take off your stainless steel wedding ring, and electrical discharges leave a lot of black carbon-like crap all over your ring when it's done shocking the hell out of you.