I've had this issue for a long time now, and I cannot figure out what exactly is causing it.
I leave my computer on 24/7, and turn my monitors off whenever I leave my desk. Whenever I come home and turn my monitors on, my computer seems to lock up for a few seconds and the monitors flicker until the resolution can display properly. Once they are displaying, there is not really any issues afterwards. (Sometimes when I launch a game, the same issue may happen but its not that common).
The current monitors I have are Asus - VG278 x 2 (One using Display Port, one using DVI-Dual Link, this is my left monitor, and right monitor)
My monitor in the center is an Asus ROG Swift PG278QR using DIsplay Port
My computer Specs
GPU - EVGA GeForce GTX 1080 Ti FTW3 ELITE
CPU - i9-9900k
MOBO - Asus ROG Strix Z390-E
I am not sure if this has anything to do with two monitors being 1080p, and one being 1440p.
Any help would be appreciated