First I am on a budget but I do plan on upgrading components as I can.
I am not sure if I want to go AMD or Nvidia at this time but I have seen many impressive reviews of AAA titles with Nvidia.
The only reason why I would consider AMD is to possibly use the same build as a Hackintosh (if I can get DUAL Boot, that would be awesome)
So my biggest issue is choosing the motherboard and case. I know once these two are selected, everything else will be more streamlined.
For the motherboard, I would love to have as many expansion slots as possible and definitely want to support Thunderbolt 3 (at least 2)
RGB lightning is not a concern for me. My computer will be hidden away in an area where it can get as much air as necessary (so fancy RGB lights isn't something I am looking for).