dude you don't have to go for all 4 channels but remember to put the ram on channles 2 and 4 or 1 and 3. that way you'll get max performance :)) don't go for quad channel for a 16gb. go for 32gb quad channel later on as an upgrade :)) and I would actually suggest getting NZXT Kraken x52 or x62 for the AIO. I don't really suggest thermaltake and don't go for RGB too much. sometimes simple lightings on a setup looks better I'm going for a all black setup but with white led lightings. I like to keep my stuff modern so I don't want to overuse RGB although I'm getting trident z rgb 16gb but aircooled cpu