I've assembled/disassembled/modified this loop a few times and the temperatures have never really changed. Originally it was just a 280mm rad for the CPU alone, then added the GPU and a 420mm radiator, and I've noticed that the last radiator takes significantly longer to fill than the first, in spite of requiring a much smaller volume of water. I once had a second Poseidon 1080 Ti in the loop, but the cooler was defective (92C on water with all fans at 100%) so I had to send it back, and haven't found it back in stock since. Even then, the temps on the original Poseidon didn't change, and the GPUs were in parallel.