If your cooling is adequate and you have a good PSU and you have money to spend then it is worth it but if you don't then its probably best to go with the 1650
If your looking for power go with the Titan. If your looking for a cost-effective option go with the 1650.
Read more information here :
https://gpu.userbenchmark.com/Compare/Nvidia-GTX-Titan-vs-Nvidia-GTX-1650/2191vs4039