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Parideboy

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  1. Agree
    Parideboy reacted to Brooksie359 in AMD gaming/streaming config   
    The 7600x and 7700x are both really good at gaming and at 4k the gpu matters way more so unless they can afford to upgrade the cpu without having to get a cheaper gpu I would prioritize the gpu for sure. 
  2. Like
    Parideboy reacted to Skiiwee29 in FanControl, my take on a SpeedFan replacement   
    Whelp.. @Rem0o get ready for your downloaded numbers to jump drastically. 
     
     
  3. Informative
    Parideboy reacted to captain_to_fire in COVID-19 - READ THE RULES BEFORE REPLYING   
    The main purpose of vaccination is that the body will now quickly ramp up production of antibodies that will neutralize the virus in a matter of few hours instead of weeks with natural infection. Of course, severely immunocompromised people such as those with AIDS, chemo/radiation patients, and other severe comorbidities would have a slower immune response despite getting vaccinated but it will still offer some protection. That's why these people should consult with their doctors on when and how to schedule their vaccinations. As someone with an autoimmune disease, my rheumatologist picked the proper drug for me that is specific to my illness but not to the normal immune response pathways, including B-cell activation.
     
    Once vaccinated, the immune system's cells called sentinels called "dendritic cells" pick up the active components of the vaccine (e.g. lipid encapsulated mRNA, adenovirus containing spike protein cDNA, or whole dead virus), process it, and then travel to the nearest lymph nodes like the ones in the armpit. (few days) Once inside the lymph nodes, the dendritic cells present the processed spike protein antigen to Helper T cells. (few days) Activated Helper T cells prime other immune cells such as B cells which produces antibodies, and killer T cells which kills infected cells. Few days post vaccination, B cells now clone themselves into Plasma cells which now started to produce IgM which is a good complement activator, but not that good for an antivirus response. Which is why vaccinated individuals should still limit going outside and wear masks because the immune response is not yet robust few days post-vaccination. 10-14 days after vaccination, the B cells undergo class switching as signaled by substances secreted by other immune cells. B cells will clone again to plasma cells, but this time these plasma cells will now produce IgG molecules which what we want for a strong antiviral response. Also, B cells clone into memory B cells which confers lasting immunity. So if you got exposed to the real SARS-Cov-2, your memory B cells will clone into plasma cells in a matter of few hours and start producing IgG antibodies that latch on to the spike protein in the coronavirus surface. IgG bound viruses are incapable of infecting ACE2 expressing cells, and antibodies signal other cells such as macrophages to gobble up and destroy the virus. The reason why some vaccines need booster doses is to create a much stronger immune response as plasma cells will eventually die out after a few weeks and to create more memory B and T cells. This is just my personal opinion but I really hope JNJ considers making a booster dose because coronaviruses mutate though not as fast as the flu virus. If the spike protein gene sustains enough mutations, that can eventually lead to a complete antibody escape, thus making the vaccine useless. So far, most of the vaccines still confer protection even to the delta variant and most of the people dying from it are unvaccinated individuals. The most important mindset is that the vaccine may not be able to completely prevent me from being infected, but it will prevent me having severe complications leading to death. Antibodies generated from the vaccine simply raise the threshold before someone gets sick.
  4. Agree
    Parideboy reacted to captain_to_fire in COVID-19 - READ THE RULES BEFORE REPLYING   
    How I wish it was indeed an aura we can emit lol. 😂 
     
    It’s actually quite sad because there are people in my community who wouldn’t get it because of extremely rare adverse reactions like the CVT with thrombocytopenia associated with JNJ and AZ vaccines. But it’s important to explain the risk-to-benefit ratio which is used by doctors when deciding which drugs and procedures to give their patients. Even lay people can do the explaining. Sure, there is an extremely small risk that few individuals could develop blood clots with adenovirus based vaccines, or myocarditis with mRNA based vaccines, but the chances of developing blood clots and myocarditis and dying with those when getting infected with Covid-19 is significantly much higher.
  5. Like
    Parideboy got a reaction from Commodus in COVID-19 - READ THE RULES BEFORE REPLYING   
    Yesterday I got my second dose of the vaccine. I had the option to choose between Moderna and AstraZeneca, I've decided to go for the latter since it's the one I started with, just to be on the safe side. Never cared too much about which one to do, I'm in my 20s and I don't have any major conditions besides some minor allergies.
     
    I figured "if it's being distributed it has to be good enough not to kill me" lol
    Plus, as @tikker said, any protection is better than none. We'll all be getting another dose in 9 months anyway.
    So I just did what was available at the time.
     
    I did the first dose on the 30th of May, man was it brutal. After about 12h since the injection, I started to feel some side effects like headaches and fever (probably the worst I had in my life) but I could still move my arm just fine. Luckily for me, it all started near bedtime, so I decided to just sleep over it. The following morning I just had a minor fever that eventually went away in an hour or so.
     
    So far the second dose has been great, with no side effect after 30 hours since the injection. Arm hurts a little, but nothing that prevents me from moving it freely.
     
    There are still lots of misconceptions regarding the vaccine. I have colleagues in the 30s-40s range that still don't have the first dose because they're "waiting".
    I don't know exactly for what, but they sure are waiting 🤣
  6. Agree
    Parideboy reacted to tikker in COVID-19 - READ THE RULES BEFORE REPLYING   
    Something that also helped tremendously was that it isn't an unknown virus. It's a variant of the known coronavirus, so we had experience from things like MERS and SARS to build upon
  7. Agree
    Parideboy reacted to WkdPaul in COVID-19 - READ THE RULES BEFORE REPLYING   
    Was just reading something on COVID, and I realized people don't understand how infection and vaccines work.
     
    Getting the vaccine doesn't mean it will stop the virus from entering your body, that's obvious that's not how vaccines work; vaccines don't create an aura around you that stop infections from getting inside you, that's the job of the masks to do that !
     
    Getting the vaccine means your body will be able to identify and combat the virus when you're infected ... but somehow it seems that people don't understand that when you're infected, you'll have the anti-bodies to fight it and won't be a major vector of infection, if at all.
  8. Agree
    Parideboy reacted to tikker in COVID-19 - READ THE RULES BEFORE REPLYING   
    I think (but I could be wrong) there are a lot of misconceptions that the speed at which it was developed and deployed means it is a rushed vaccine that we know nothing about, so they want proper testing. It is true that mRNA vaccines are new, and that there was an accelerated procedure to get it out, but it was a global emergency and we're not injecting just some random thing. I say we've had our baptism of fire. Whatever the opinion, any serious highly dangerous or lethal side-effects would have shown up by now. In fact they have, with these very rare thrombosis cases and such.
     
    Personally I don't see how "yeah we're just injecting a live virus to teach your body how to fight it" (normal vaccine) sounds less scary then "we're just injecting information how to fight the virus in a format the body understands" (mRNA).
  9. Agree
    Parideboy reacted to tikker in COVID-19 - READ THE RULES BEFORE REPLYING   
    This is the right attitude to have. Even if it "only" has 70% or so effectiveness or is less effective against some variants, that is still infinitely better than 0% from no vaccine at all. One of the reasons why there's a flu shot every year is exactly because the virus is constantly changing and old vaccines won't be (as) effective anymore. Effectiveness is nothing new. Communicating that less protection doesn't mean no protection can be difficult though.
     
    People's perception of numbers is also often biased towards negatives in my experience. For example instead of seeing a potential of reducing infection and severe symptoms by 70%, you focus on the 30% chance that it doesn't. Instead of seeing the good it does, you focus on the 0.00000001% of a certain potentially lethal side-effect. The problem with the latter is that since we're vaccinating on such a massive scale even the rarest and most exotic side-effects will show up.
  10. Funny
    Parideboy reacted to captain_to_fire in COVID-19 - READ THE RULES BEFORE REPLYING   
    Just got the JNJ single shot Covid-19 vaccine two days ago, after weeks of struggling to register. Getting vaccinated is not something new to me even as an adult because I get annual flu shots, I got the pneumococcal (PCV13) shot last year (painful in the arm for two days because it’s viscous), and the three doses of Gardasil 9 four years ago, all without the flu-like symptoms. The JNJ vaccine was different, I got the shot at 9 am, went on with my daily routine including indoor cycling for 30 minutes at 10:30 am, and my 8 pm I got fever and a headache which lasted until the next day. It was the kind of sick feeling when you get the flu minus the sniffles and stuffed nose. 
     
    Is it my preferred vaccine? No. But the town where I’m currently residing doesn’t have an ultra-low freezer to store the two mRNA vaccines so I sticked to the adenovirus based vaccine from Janssen and I gotta take what’s available. Some people might say that the JNJ vaccine doesn’t offer robust protection against the delta variant based on this new study which contradicts Janssen’s statement, but assuming that is true it’s not like the OG SARS-Cov-2 strain disappeared and got replaced with pure delta variant only. The JNJ vaccine still works against other mutations like 🇧🇷🇿🇦 and reduce mortality. I’d wait for other studies to corroborate NYU’s findings, and if so hopefully Janssen makes a booster shot similar to AstraZeneca and Sputnik V. 
     
    Nonetheless, I am now a walking JNJ 5G tower and I emit central venous thrombosis with thrombocytopenia and scare the crap out of Karens. 
  11. Like
    Parideboy got a reaction from WhitetailAni in Folding Community Board   
    Thanks, everyone. I ran Heaven and Superposition for a couple of hours without any issue.
    In the end, it was F@H. The client got stuck somehow, simply killing it from task manager solved the issue.
    Dealing with a dead gpu now would have been ... less than ideal, to say the least.
  12. Like
    Parideboy got a reaction from WhitetailAni in Folding Community Board   
    Anyone having problem on AMD cards lately? WU are failing, even on stock settings
  13. Like
    Parideboy reacted to GOTSpectrum in Mid-week Madness Folding Sprint   
  14. Like
    Parideboy reacted to GOTSpectrum in Mid-week Madness Folding Sprint   
  15. Like
    Parideboy reacted to Shlouski in Mid-week Madness Folding Sprint   
    Today's new arrival enters the fold 😄
     

     
  16. Like
    Parideboy got a reaction from Pezui in Mid-week Madness Folding Sprint   
    Just tried playing Yakuza kiwami while folding. It works @60+ fps. My life is complete now.
    Nice! I can probably shave a couple more degrees by using noctua fans and applying some thermal pads between the backplate and the back of the card. I already flashed a modded bios to try some serious oc 👀
     
    (I applied new thermal paste a couple of months ago. I was hitting the low 90s before, dropped to the low 80s afterwards)
  17. Like
    Parideboy reacted to Captainmarino in Mid-week Madness Folding Sprint   
    Same here on all fronts. First, I took off the heatsink and found the thermal compound to be rock solid. Chiseled that away, applied some new stuff and BAM 15 degrees lower even with a single fan hobbling along. Took both the dead and decrepit fans off, zipped a couple of 80s(?) on there and went from an original ~90 degrees (pre-compound and fans) down to 60-65.
  18. Like
    Parideboy got a reaction from Pezui in Mid-week Madness Folding Sprint   
    That's what I ended up doing lol. Grabbed 2 bequiet 120mm fans I had laying around, zip-tied those bad boys and not only the card got quieter, also the die temp dropped about 15c.
     
    This mod should be done out of the box if you ask me 😄
  19. Like
    Parideboy reacted to ShadowChaser in Mid-week Madness Folding Sprint   
    *glances at his p104-90 with a 92mm zip tied on* 😞 
     
    Granted it's still pulling roughly 300k PPD! Not a bad little rescue 😉 
     
    And my pride and joy(s), dual Tesla M40s that cost me $1.30 to run everyday, but it's for a good cause!

  20. Like
    Parideboy reacted to GOTSpectrum in Mid-week Madness Folding Sprint   
    Shit sorry guys, I'm not gonna lie to you lot. I got a vegetarian kebab on friday and I've been rather unwell for the last few days! 
     
    Only today have I realised what day it was!!! 
     
    But I'm here and I'm alive! 
  21. Like
    Parideboy got a reaction from Captainmarino in Mid-week Madness Folding Sprint   
    That's what I ended up doing lol. Grabbed 2 bequiet 120mm fans I had laying around, zip-tied those bad boys and not only the card got quieter, also the die temp dropped about 15c.
     
    This mod should be done out of the box if you ask me 😄
  22. Like
    Parideboy got a reaction from Baha in Mid-week Madness Folding Sprint   
    That's what I ended up doing lol. Grabbed 2 bequiet 120mm fans I had laying around, zip-tied those bad boys and not only the card got quieter, also the die temp dropped about 15c.
     
    This mod should be done out of the box if you ask me 😄
  23. Funny
    Parideboy got a reaction from piratemonkey in Mid-week Madness Folding Sprint   
    *looks at his 390 with a rattling fan* ☹️
  24. Like
    Parideboy reacted to Captainmarino in Mid-week Madness Folding Sprint   
    I've still got a 280 folding and it had been limping along on one fan while the other was frozen stiff with arthritis. It's since been given replacement hips held on by zip ties 😄
  25. Like
    Parideboy reacted to justpoet in Mid-week Madness Folding Sprint   
    *cries in CPU only*
    I'd use my M370X, but they don't support Mac OS for GPU. 😞
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