It'll run, how well depends on hardware choices.
Your single ram stick holds you back a decent amount from what you SHOULD be getting on AVG.. let alone 2133Mhz being quite slow, esp for Ryzen systems, its also single channel with a single stick, you've already (at lower settings in game to enhance framerates) lost 20-odd Percent Performance (at least) from using 1 stick (Single Channel) over 2 sticks Dual Channel.
Highly recommend getting 2 sticks of 3000-3200Mhz, as the Ryzen 2nd gen CPU speed is tied in a sense to the RAM speed via Fabric speed (Internal CPU Communication between RAM & CPU)
Higher Ram speed = Higher Fabric speed (vice versa), 1st and 2nd Gen fabric clocks not as compatible with getting the higher speeds like 3rdGen/5thGen Ryzen (3200-4000Mhz Ram) But 3000-3200 should be quite compatible with 2nd Gen Ryzen.
But its having DUAL CHANNEL that matters the most (Dual Sticks, Matched Timings and Paired, basically Dual-Channel Kits you can buy) you can buy these simple as a 2x8GB or 2x16GB capacities of such speeds.
RX6600 will easily max the game out, or use lower settings for higher FPS, but your RAM right now....holds all that back...