There appears to be an issue with windows 10 (mostly running x64) and the drivers for AMD Radeon R9 series cards.
https://community.amd.com/thread/230393
sadly no matter any work around I have tried, if the driver updates it proceeds to give a “Black screen of death” causing the system to lock up, and when rebooted will hang Win 10 at boot.
The card works just fine in safe mode, and when no driver is installed.
Installing driver direct from AMD does not fix problem either.