I have a 39" seiki 4K tv (120hz in 1080p, 72hz 1440p, 33hz 4K) and 2 60hz 21.5" LG monitors on either side in portrait - they are the same width as my TV is high. I'm running all three of those on one XFX r9 270x... I'm really interested about getting an rx 480 to see if they support portrait-landscape-portrait (PLP) display set ups like I have. I also know that the r9 285, 380, 380x, fury and nano all support PLP and other mixed resolution display groups with eyefinity (this is because of gcn 1.2 but I don't know if that's what the 480 uses or not). I just got back to work after a year off, so I am planning to buy one but can't afford it yet... I'll make a video of my excursion for the forums :3 (it will probably be terrible).