VincentN

H110 does not support NVMe. It is also important to note that if you do populate an M.2 drive it will use some SATA ports, so you may need to move the existing HDD to other SATA ports on the motherboard if it stops getting detected.
 
I would honestly just get a 2.5" SATA SSD, they're cheaper and wont steal any PCI-E lanes (H110 only has 6 lanes maximum).