Akikai

A few things are mixed together:
- ASIO is restricted to a single application keeping control over a device (low latency low level access). You can't use different applications at the same time to output and input audio via ASIO.
- You probably set the sample rate and bit depth to different values for the input and the output of the UMC22. These have to be identical or it won't work.
 

 
I would recommend to delete any driver of the UMC22 from you computer, do a fresh reinstall and look through all the settings.

I'm going to edit this and throw a R7 1700 in. K?
PCPartPicker part list / Price breakdown by merchant
CPU: AMD - Ryzen 7 1700 3.0GHz 8-Core Processor  ($299.89 @ OutletPC) 
CPU Cooler: NZXT - Kraken X62 Liquid CPU Cooler  ($158.99 @ SuperBiiz) 
Motherboard: ASRock - Fatal1ty X370 Gaming K4 ATX AM4 Motherboard  ($138.99 @ SuperBiiz) 
Memory: G.Skill - Trident Z RGB 16GB (2 x 8GB) DDR4-3200 Memory  ($149.99 @ Newegg) 
Storage: SK hynix - SL308 250GB 2.5" Solid State Drive  ($87.88 @ OutletPC) 
Storage: Seagate - Barracuda 2TB 3.5" 7200RPM Internal Hard Drive  ($73.88 @ OutletPC) 
Video Card: Asus - GeForce GTX 1080 Ti 11GB STRIX GAMING Video Card  ($739.88 @ OutletPC) 
Case: NZXT - S340 Elite (Black) ATX Mid Tower Case  ($98.99 @ SuperBiiz) 
Power Supply: EVGA - SuperNOVA G2 650W 80+ Gold Certified Fully-Modular ATX Power Supply  ($79.87 @ Amazon) 
Monitor: AOC - AG271QG 27.0" 2560x1440 165Hz Monitor  ($614.64 @ B&H) 
Total: $2443.00
Prices include shipping, taxes, and discounts when available
Generated by PCPartPicker 2017-06-04 22:06 EDT-0400

As long as it doesnt hit the ceiling. 46°C is still relatively cool

Replace the 8350 with a i5-6500 or so and get a really cheap B150/H110/H170 motherboard and you'll get more performance in most games nowadays. Also, it's cheaper to get a single 16GB kit of RAM. Another thing, get a decent PSU from tiers 1 to 3 on this list:
 

Get an i5 6500 with H170/B150 mobo and DDR4. That PSU isn't the best either. What country are you in? 

Here is a list with a better proccesor, boot SSD and it's cheaper. Also, removed the aftermarket cooler because the stock one is fine since you can't overclock. Don't know why people are hating on Be Quiet PSUs, they are a pretty good brand but I changed it to Corsair anyways.
 
 
PCPartPicker part list / Price breakdown by merchant
CPU: Intel Core i5-6500 3.2GHz Quad-Core Processor  (€195.69 @ Mindfactory) 
Motherboard: Asus H110M-A D3 Micro ATX LGA1151 Motherboard  (€61.20 @ Amazon Deutschland) 
Memory: PNY Anarchy 16GB (2 x 8GB) DDR3-2400 Memory  (€84.14 @ Amazon Deutschland) 
Storage: PNY CS1311 120GB 2.5" Solid State Drive  (€46.04 @ Amazon Deutschland) 
Storage: Western Digital Caviar Blue 1TB 3.5" 7200RPM Internal Hard Drive  (€49.00 @ Amazon Deutschland) 
Video Card: Gigabyte GeForce GTX 1060 3GB 3GB Windforce OC Video Card  (€219.29 @ Mindfactory) 
Case: Fractal Design Core 2300 ATX Mid Tower Case  (€48.89 @ Amazon Deutschland) 
Power Supply: Corsair CX 500W 80+ Bronze Certified Semi-Modular ATX Power Supply  (€73.84 @ Mindfactory) 
Total: €778.09
Prices include shipping, taxes, and discounts when available
Generated by PCPartPicker 2016-11-12 22:11 CET+0100
 

The 1060 3gb is cheaper, more powerful and just all around a better choice.