yeah but u would be kinda "bottlenecking" the 750Ti so try a i5-4670k for around $250 or go up noch and get i5-4690k for around the same price and get 0.1Ghz improvement and some other things as well, anyways pair any of these with the 750Ti and you're golden but if u need more pay around double the price of the 750Ti and get a power monster a gtx 970 factory oc for around $350 from EVGA. a GTX 970 with i5-4670k/4690k you can run almost any game at medium to high settings at 1440p BUT IF YOU WANT TO GO WITH A CORE i3 AND GTX 750Ti THEN THAT IS ABSOLUTELY FINE AS WELL IT IS YOUR CHOICE.